TABLE 2

Pharmaceutical Treatments Administered in the ED for Migraine to 32 124 Children Aged 7 to 18 Years Across 35 Academic Children’s Hospitals, 2009–2012

All Patients, n = 32 124, n (%)Discharged Patients, n = 27 317, n (%)Admitted Patients, n = 4807, n (%)
Medication classes (not mutually exclusive)
 Nonopioid analgesics21 077 (65.6)17 530 (64.2)3547 (73.8)
 Dopamine receptor antagonists16 019 (49.9)13 258 (48.5)2761 (57.4)
 Diphenhydramine10 659 (33.2)8605 (31.5)2054 (42.7)
 Ondansetron6774 (21.1)5128 (18.8)1646 (34.2)
 Antiepileptic agents2931 (9.1)1238 (4.5)1693 (35.2)
 Corticosteroids2020 (6.3)1291 (4.7)729 (15.2)
 Opioids1800 (5.6)1080 (4.0)720 (15.0)
 Triptans1032 (3.2)876 (3.2)156 (3.3)
 Dihydroergotamine mesylate997 (3.1)159 (0.6)838 (17.4)
Most common treatment regimens
 No treatment6284 (19.6)5820 (21.3)464 (9.7)
 Dopamine antagonists and nonopioid analgesics4495 (14.0)4263 (15.6)232 (4.8)
 Dopamine antagonists, nonopioid analgesics, and diphenhydramine4061 (12.6)3771 (13.8)290 (6.0)
 Nonopioid analgesics3240 (10.1)2929 (10.7)311 (6.4)
 Analgesics and ondansetron1921 (6.0)1774 (6.5)147 (3.1)
 Dopamine antagonists and diphenhydramine1160 (3.6)1108 (4.1)52 (1.1)
 Dopamine antagonists877 (2.7)837 (3.1)40 (0.8)
 Analgesics, ondansetron and diphenhydramine823 (2.6)764 (2.8)59 (1.2)
 Dopamine antagonists, analgesics, antiepileptics, and diphenhydramine715 (2.2)394 (1.4)321 (6.7)