TABLE 4

Comparison of Standardized Rates for Major Neonatal Morbidities in 2000 and 2009 for Surviving Infants 501 to 1500 g

2000, %2009, %Difference (95% CI)
Any major morbidity
 All 501–1500 g46.441.4−4.9 (−5.6 to −4.2)
 501–750 g84.582.7−1.8 (−3.4 to −0.3)
 751–1000 g63.157.4−5.6 (−7.2 to −4.1)
 1001–1250 g38.833.1−5.7 (−7.1 to −4.3)
 1251–1500 g23.318.7−4.6 (−5.8 to −3.5)
Major neonatal morbidities
 Early bacterial infection2.01.7−0.3 (−0.6 to −0.1)
 Late infection (bacterial or fungal)21.515.0−6.6 (−7.2 to −6.0)
 NEC4.95.30.4 (0.0 to 0.7)
 CLD27.726.3−1.4 (−2.1 to −0.8)
 Severe IVH (grades 3 and 4)6.56.1−0.4 (−0.8 to 0.0)
 PVL3.02.7−0.3 (−0.6 to −0.0)
 Severe ROP (stages 3–5)10.26.8−3.3 (−3.8 to −2.8)
  • Adjusted for infant characteristics based on logistic regression. Values are computed by using the characteristics of infants born in 2009 as the reference population.