TABLE 3

Improvement in Efficacy Assessments From Baseline to Week 5

Efficacy AssessmentPlacebo Plus Stimulant (n = 95)CLON-XR Plus Stimulant (n = 102)P
ADHD-RS-IV, mean (SD)
    Total change−11.5 (12.2)−15.7 (12.3).009
    Inattention subscale−5.8 (6.8)−7.8 (6.8).017
    Hyperactivity/impulsivity subscale−5.8 (6.3)−7.9 (6.7).014
CPRS, mean (SD)
    Total change−27.1 (38.2)−40.2 (41.4).017
    Hyperactivity subscale−3.8 (5.7)−5.8 (6.5).017
    Oppositional subscale−3.6 (6.3)−5.1 (6.6).062
CGI-S, mean (SD)−1.2 (1.3)−1.5 (1.2).021
CGI-I, mean (SD)3.0 (1.2)2.5 (1.2).006
PGA, mean (SD)3.4 (1.4)2.7 (1.3).001