TABLE 1

Pathogens Associated With EOS and EOM

PathogenEOSaEOMb
n%n%
Gram-positive23162850
    GBS15943319
    Viridans group streptococci205213
    S aureusc9216
    Enterococci10316
    Group A streptococci92
    Coagulase-negative staphylococcid3<1
    Other Gram-positivee21616
Gram-negative13737850
    E coli10729744
    Haemophili113
    Other Gram-negativef19516
Fungi2<1
    Candida albicans2<1
Total37010016100
  • a Data were excluded from 12 infants whose blood culture results were positive for the following polymicrobial infections: GBS + E coli (3); enterococci + CoNS (2); Neisseria species + haemophili (1); Neisseria species + Viridans group streptococci (1); klebsiella + Candida albicans (1); Pseudomonas aeruginosa + Enterobacter species (1); Group A streptococci + CoNS (1); Viridans group streptococci + CoNS (1), Serratia species + enterococci (1).

  • b Data were excluded from 1 infant with a polymicrobial infection on CSF culture that was considered a true infection by the attending physician (Acinetobacter species + micrococci) and a negative blood culture. Among the remaining 16 infants with EOM, 10 infants had blood and CSF cultures that were positive for the same organism: GBS (2); Viridans group streptococci (1); E coli (7); and 6 infants had negative blood cultures and positive CSF cultures: 1 each for GBS, S aureus, Viridans group streptococci, α streptococci, enterococci, and klebsiella).

  • c One infant with methicillin-resistant S aureus was identified.

  • d These infants had >1 positive blood culture for CoNS.

  • e Organisms found in blood culture: α-hemolytic Streptococcus (1); Streptococcus pneumoniae (4); Group D Streptococcus (1); Streptococcus bovis/gallolyticus (4); bacilli (4); Listeria monocytogenes (2); Actinomyces odontolyticus (1); Gram-positive rods, CDC group A (1); Gram-positive cocci in chains and pairs (1); non–spore-forming Gram-positive rod (1); aerobic Gram-positive bacilli, not listeria/erysipelothrix/bacillus (1). Organisms found in CSF culture: α-hemolytic Streptococcus (1).

  • f Organisms found in blood culture: Enterobacter species (3); Citrobacter species (2); Acinetobacter species (1); klebsiella (1); Pseudomonas aeruginosa (1); bacteroides (3); Moraxella species (1); Morganella species (5); Capnocytophaga species (2). Organisms found in CSF culture: klebsiella (1).