TABLE 4

Potential Pharmaceutical Supplement Interactions With Energy Drink Ingredients30,82,83

Energy Drink IngredientInteractions
5-Hydroxy tryptophanShould not be combined with monoamine oxidase inhibitors
VinpocetineIncreases the risk for excessive bleeding and should not be combined with aspirin, clopidogrel, warfarin, pentoxifylline, vitamin E, garlic, and gingko
YohimbineAffects cardiac function and should not be combined with tricyclic antidepressants, bupropion, phenothiazines, clonidine, stimulants, decongestants, or other blood pressure-lowering medications
GinsengProlongs bleeding time and should not be combined with warfarin; interacts with phenelzine sulfate in patients being treated for mania; may interfere with estrogens or corticosteroids; may impede digoxin metabolism; reduces blood glucose levels