TABLE 1

Demographic Characteristics and Medical History of Children Who Presented to the ED With a Food-Related Acute Allergic Reaction

Overall (N = 1255), % (95% CI)No Anaphylaxis (N = 597), % (95% CI)Anaphylaxis (N = 658), % (95% CI)aP
Demographic characteristic, n (%)
    Age, median, y (95% CI)5.8 (5.3–6.3)4.8 (4.1–5.45)6.7 (5.9–7.4).003
    Male62 (57–66)62 (55–69)62 (56–68).97
    Race/ethnicity.02
        White40 (35–44)31 (25–38)47 (41–53)
        Black27 (23–32)31 (24–38)24 (19–29)
        Hispanic12 (9–16)16 (10–22)9 (6–12)
        Asian9 (6–12)10 (5–14)8 (5–12)
        Other race12 (8–15)12 (7–17)12 (7–16)
Medical history, n (%)
    Known allergy to offending allergen41 (36–46)37 (29–44)44 (38–51).11
    Known allergic problems67 (63–72)56 (49–64)77 (73–82)<.001
        Previous allergic reactions to other sources62 (57–68)59 (49–69)64 (57–71).39
        Asthma41 (35–47)31 (22–40)48 (40–55).008
        Hay fever20 (15–25)16 (8–23)23 (16–29).16
        Eczema33 (27–39)37 (27–47)31 (24–37).33
        Hives1 (0–2)2 (0–5)0.12
        Angioedema000
    Patient owns EpiPen40 (34–45)30 (23–37)48 (41–55).001
    Other documented medical problems11 (8–14)9 (5–14)13 (9–17).25
    Patient on any chronic medications37 (33–42)26 (19–32)48 (42–55)<.001
  • a Anaphylaxis was defined as an allergic reaction involving ≥2 organ systems or hypotension. Hypotension was defined as systolic blood pressure of less than (70 + [age ×2]) for children younger than 10 years and systolic blood pressure of <90 mm Hg for children aged 10 to 18 years.