TABLE 1

Characteristics of Children Hospitalized With Acute Respiratory Illness Overall and by Influenza Positivity and Influenza Vaccination Status (Documentation Supplemented by Parental Report), NVSN, 2018–2019

CharacteristicNo. Enrolled, n (%)Influenza-Positive, n (%)Influenza-Negative, n (%)PVaccinated (≥1 Dose), n (%)Not Vaccinated, n (%)P
Overall179222615661070722
Sex.98.69
 Male998 (56)126 (56)872 (56)600 (56)398 (55)
 Female794 (44)100 (44)694 (44)470 (44)324 (45)
Age category<.001<.001
 6 mo to <5 y1255 (70)109 (48)1146 (73)784 (73)471 (65)
 5–17 y537 (30)117 (52)420 (27)286 (27)251 (35)
Race and/or ethnicity.004<.001
 White, non-Hispanic696 (39)104 (46)592 (38)429 (40)267 (37)
 Black, non-Hispanic423 (24)61 (27)362 (23)200 (19)223 (31)
 Other, non-Hispanic177 (10)20 (9)157 (10)103 (10)74 (10)
 Hispanic496 (28)41 (18)455 (29)338 (32)158 (22)
Underlying medical conditionsa.32.01
 ≥11031 (58)137 (61)894 (57)642 (60)389 (54)
 None761 (42)89 (39)672 (43)428 (40)333 (46)
Hospitalization in past year.27<.001
 01093 (61)144 (64)949 (61)609 (57)484 (67)
 ≥1685 (38)82 (36)603 (39)451 (42)234 (32)
 Unknown14 (1)0 (0)14 (1)10 (1)4 (1)
Surveillance site<.001<.001
 Cincinnati133 (7)22 (10)111 (7)65 (6)68 (9)
 Houston471 (26)45 (20)426 (27)341 (32)130 (18)
 Kansas City137 (8)7 (3)130 (8)59 (6)78 (11)
 Nashville275 (15)24 (11)251 (16)136 (13)139 (19)
 Pittsburgh448 (25)84 (37)364 (23)247 (23)201 (28)
 Rochester113 (6)14 (6)99 (6)69 (6)44 (6)
 Seattle215 (12)30 (13)185 (12)153 (14)62 (9)
Insurance status.45<.001
 Public (or none or self-pay)1169 (65)148 (65)1021 (65)660 (62)509 (70)
 Private or both605 (34)74 (33)531 (34)403 (38)202 (28)
 Unknown18 (1)4 (2)14 (1)7 (1)11 (2)
Days of symptoms since illness onset.73.07
 0–2717 (40)96 (42)621 (40)430 (40)287 (40)
 3–4561 (31)64 (28)497 (32)353 (33)208 (29)
 5–7384 (21)48 (21)336 (21)220 (21)164 (23)
 8–10130 (7)18 (8)112 (7)67 (6)63 (9)
Received mechanical ventilation88 (5)12 (5)76 (5).9451 (5)37 (5).62
Death7 (<1)1 (<1)6 (<1)5 (<1)2 (<1)
  • a Comorbid conditions obtained from medical chart review included chronic pulmonary and/or airway, cardiac, gastrointestinal, kidney, endocrine, neurologic and/or neuromuscular, developmental, hematologic and oncologic, genetic and/or metabolic, and immunocompromised conditions; pregnancy; and prematurity.