TABLE 2

Maternal Characteristics of 15 041 Pregnancies With an Antidepressant Claim in the First 35 Weeks’ Gestation Between 2012 and 2016 in OLDW

35-wk Trajectory Group
Low Use With Reduction (A), n = 7622Low Sustained Use (B), n = 3170Moderate Use With Reduction (C), n = 1907Moderate Sustained Use (D), n = 1918High Sustained Use (E), n = 424
Maternal age, y
 <25 y269 (3.5)69 (2.2)44 (2.3)18 (0.9)<11 (<2.6)
 25–34 y4942 (64.8)1936 (61.1)1146 (60.1)1101 (57.4)>224 (>52.8)
 >34 y2411 (31.6)1165 (36.8)717 (37.6)799 (41.7)189 (44.6)
No. births in study period
 17065 (92.7)2915 (92.0)1797 (94.2)1761 (91.8)384 (90.6)
 2+557 (7.3)255 (8.0)110 (5.8)157 (8.2)40 (9.4)
Maternal race
 White6148 (80.7)2738 (86.4)1585 (83.1)1676 (87.4)365 (86.1)
 African American503 (6.6)140 (4.4)124 (6.5)80 (4.2)23 (5.4)
 Hispanic643 (8.4)155 (4.9)119 (6.2)93 (4.9)24 (5.7)
 Other or unknown328 (4.3)137 (4.3)79 (4.1)69 (3.6)12 (2.8)
Education
 Less than or equal to high school degree or unknown1400 (18.4)427 (13.5)358 (18.8)236 (12.2)46 (10.9)
 Less than bachelor’s degree4401 (57.7)1825 (57.6)1062 (55.7)1091 (56.9)244 (57.6)
 Bachelor’s degree or higher1821 (23.9)918 (29.0)487 (25.5)591 (30.8)134 (31.6)
Comorbidities and coexposuresa
 Depression diagnosis2270 (29.8)1279 (40.4)812 (42.6)932 (48.6)282 (66.5)
 Anxiety diagnosis2838 (37.2)1406 (44.4)867 (45.5)924 (48.2)258 (60.8)
 Other mental health diagnosis1360 (17.8)754 (23.8)429 (22.5)506 (26.4)157 (37.0)
 Pain diagnosis1349 (17.7)514 (16.2)355 (18.6)345 (18.0)104 (24.5)
 Sleep disorder diagnosis427 (5.6)145 (4.6)133 (7.0)109 (5.7)33 (7.8)
 Hypertension210 (2.8)73 (2.3)62 (3.3)63 (3.3)13 (3.1)
 Antipsychotics55 (0.7)44 (1.4)52 (2.7)74 (3.9)40 (9.4)
 Benzodiazepines657 (8.6)292 (9.2)280 (14.7)269 (14.0)112 (26.4)
  • All data are presented as n (%). Cell sizes <11 are suppressed per requirements of OptumLabs.

  • a Prescription fills through 35 wk gestation.