TABLE 1

Estimated 1-Dose and 2-Dose VE Estimates Against Notified Rotavirus in Children Aged 6 Months to 9 Years in 2017 Compared to the 2010–2016 Period, New South Wales

CohortCase PatientsControlsVE (95% CI)
2017
 All ages (6 mo–9 y), n103110 300
  Unvaccinated, n (%)295 (28.6)697 (6.8)Reference
  1-dose vaccinated, n (%)44 (4.3)593 (5.8)83.0 (76.2 to 87.9)
  2-dose vaccinated, n (%)692 (67.1)9010 (87.5)82.5 (79.4 to 85.1)
   Aged 6–11 mo, n91900
    Unvaccinated, n (%)26 (28.6)44 (4.9)Reference
    1-dose vaccinated, n (%)5 (5.5)40 (4.4)80.3 (43.1 to 93.2)
    2-dose vaccinated, n (%)60 (65.9)816 (90.7)88.4 (79.2 to 93.5)
   Aged 1–3 y, n6256254
    Unvaccinated, n (%)161 (26.9)331 (5.3)Reference
    1-dose vaccinated, n (%)26 (4.2)360 (5.8)84.9 (76.6 to 90.3)
    2-dose vaccinated, n (%)438 (70.1)5563 (89.0)83.7 (79.8 to 86.8)
   Aged 4–9 y, n3153146
    Unvaccinated, n (%)108 (34.3)322 (10.2)Reference
    1-dose vaccinated, n (%)13 (4.1)193 (6.1)80.7 (64.5 to 89.5)
    2-dose vaccinated, n (%)194 (61.6)2631 (83.6)78.7 (72.1 to 83.7)
2010–2016
 All ages (6 mo–8 y), n255625 529
  Unvaccinated, n (%)671 (26.3)2599 (10.2)Reference
  1-dose vaccinated, n (%)170 (6.7)1628 (6.4)60.4 (52.5 to 66.9)
  2-dose vaccinated, n (%)1715 (67.1)21 302 (83.4)69.5 (66.3 to 72.4)
   Aged 6–11 mo, n3973945
    Unvaccinated, n (%)127 (32.0)371 (9.4)Reference
    1-dose vaccinated, n (%)31 (7.8)276 (7.0)68.9 (52.3 to 79.8)
    2-dose vaccinated, n (%)239 (60.2)3298 (83.6)79.3 (73.6 to 83.8)
   Aged 1–3 y, n181818 174
    Unvaccinated, n (%)456 (25.1)1817 (10.0)Reference
    1-dose vaccinated, n (%)122 (6.7)1132 (6.2)57.6 (47.5 to 65.8)
    2-dose vaccinated, n (%)1240 (68.2)15 225 (83.8)68.2 (64.1 to 71.8)
   Aged 4–8 y, n3413410
    Unvaccinated, n (%)88 (25.8)411 (12.1)Reference
    1-dose vaccinated, n (%)17 (5.0)220 (6.5)64.5 (38.7 to 79.4)
    2-dose vaccinated, n (%)236 (69.2)2779 (81.5)60.9 (48.8 to 70.1)