TABLE 1

Clinical Characteristics of the Patients

CharacteristicsPatient 1Patient 2
Age at diagnosis of BD, y1515
The initial symptoms of BDAbdominal pain, fever, and hemoptysisCough, intermittent hemoptysis, fever, wt loss, and fatigue
Age at PAIAt the time of diagnosisAt the time of diagnosis
Type of PAIPAA and PATPAA
Time between BD diagnosis and PAI, mo34
Follow-up duration6 y4 y
Oral ulcer+
Genital ulcer+
PathergyNegative resultNegative result
HLA B5Negative resultPositive result
Ocular lesions
Skin involvement+
Other vascular involvementSuprahepatic VCI, vena hepatica (BCS), and RARA
ImmunosuppressionPulse methylprednisolone (intravenous), prednisolone (po), cyclophosphamide (intravenous), IFN-α2a (subcutaneous), adalimumab (subcutaneous)Pulse methylprednisolone (intravenous), prednisolone (po),cyclophosphamide (intravenous), IFN-α2a (subcutaneous), azathioprine (po)
AnticoagulationReceived anticoagulation before referral to our center
Thrombophilia
 Factor V Leiden+/−−/−
 MTHFR 677−/−+/+
 MTHFR 1298+/+−/−
 PAI-14g/4G +/+4g/4G +/+
 Antiphospholipid antibodiesNegativeNegative
Laboratory tests at the time of PAI
 WBC, cells per mm379009300
 Hb, g/dL13.19.4
 Platelets, per mm3230.000332.000
 CRP, g/dL8.54.7
 ESR, mm/h5890
  • po, per oral; −, negative; +, positive.