TABLE 1

Maternal, Child, and Medication Use Characteristics of Eligible Mothers With EDI Records of Children

CharacteristicExposed GroupUnexposed Group
Total dyads, n (%)528 (100.00)2522 (100.00)
Maternal age at birth of the index child, n (%)29.39 (5.57)27.82 (5.93)
 1922 (4.17)226 (8.96)
 20–29237 (44.89)1315 (52.14)
 30–39253 (47.92)916 (36.32)
 4016 (3.03)65 (2.58)
Place of residence, n (%)
 Urban358 (67.80)1740 (68.99)
 Rural170 (32.20)782 (31.01)
Socioeconomic status of mother at birth, mean (SD)
 SEFI-2−0.08 (0.92)0.10 (0.93)
Average age of child at time of EDI, mo, mean (SD)75.05 (5.24)74.81 (5.17)
Offspring sex, n (%)
 Male274 (51.89)1298 (51.47)
 Female254 (48.11)1224 (48.53)
Gestational age, mean (SD)
 Gestational age38.99 (1.61)39.11 (1.74)
Exposure duration of medication, mean (SD)
 No. d180.60 (100.90)
Trimester exposure, n (%)
 First trimester456 (86.36)
 Second trimester372 (70.46)
 Third trimester400 (75.76)
 First trimester only93 (17.61)
 Second trimester onlya
 Third trimester onlya
 First and second trimester only30 (5.68)
 First and third trimester only38 (7.20)
 Second and third trimester only42 (7.96)
 First, second, and third trimesters295 (55.87)
Type of serotonergic antidepressant, n (%)
 Any SSRI411 (77.84)
 Fluoxetine75 (14.21)
 Citalopram118 (22.35)
 Paroxetine128 (24.24)
 Sertraline98 (18.56)
 Fluvoxaminea
 Escitaloprama
 Any SNRI137 (25.95)
 Venlafaxine136 (25.76)
 Duloxetinea
 Desvenlafaxinea
Mood or anxiety disorder (in y before conception date)424 (80.30)1251 (49.60)
  • SEFI-2, Socioeconomic Factor Index Version 2; —, not applicable.

  • a To adhere to MCHP privacy guidelines, counts 5 and under are suppressed.