TABLE 2

Mental Health Outcomes Among Those Who Received Pubertal Suppression

Univariate AnalysesMultivariable Analyses
OR (95% CI)PaOR (95% CI)P
Suicidality, past 12 mo
 Ideation0.6 (0.4–0.8).006*0.6 (0.3–1.1)0.09
 Ideation with plan0.9 (0.5–1.6).73
 Ideation with plan and attempt1.2 (0.6–2.3).64
 Attempt resulting in inpatient care2.8 (0.8–9.4).09
Suicidality, lifetime
 Ideation0.3 (0.2–0.5)<.001*0.3 (0.2–0.6)0.001*
 Attempts0.7 (0.4–1.0).08
Mental health and substance use
 Past-month severe psychological distress, K6 ≥130.5 (0.3–0.8).001*0.8 (0.4–1.4)0.38
 Past-month binge drinking0.3 (0.8–2.0).29
 Lifetime illicit drug use1.1 (0.7–1.8).67
  • Univariate and multivariable analyses of mental health outcomes among transgender adults in the United States who ever wanted pubertal suppression when comparing those who received this treatment with those who did not. Multivariable logistic regression models were adjusted for using the demographic variables associated with each outcome at the level of P ≤ .20. Because all outcomes were associated with family support, sexual orientation, education level, employment status, and total household income, all models were adjusted for these variables. Lifetime suicide attempts were associated with gender identity, and this model was additionally adjusted for this variable. Past-month severe psychological distress and past-year suicidal ideation were additionally associated with age, gender identity, and relationship status, and thus these models were adjusted for these variables as well. Race was found to be associated with lifetime suicidal ideation and lifetime suicide attempts, and thus these models were additionally adjusted for race. Models for psychological distress and past-year suicidal ideation were also adjusted for age, gender identity, and relationship status. aOR, adjusted odds ratio.

  • a Indicates statistical significance.