TABLE 2

Associated Diagnoses of High Acuity (PECARN DGS Severity Scores 4 and 5) From Initial Visits for Infants in the 2015 and 2017 Study Cohorts

0–60 d of Age61–365 d of Age
2015 Cohort (n = 3238), n (%)2017 Cohort (n = 2270), n (%)Percentage Difference (95% CI)2015 Cohort (n = 2370), n (%)2017 Cohort (n = 1623), n (%)Percentage Difference (95% CI)
Patients with additional diagnosis954 (29.5)582 (25.6)3.8 (1.4 to 6.2)a679 (28.6)377 (23.2)5.4 (2.6 to 8.2)a
 Allergic, immunologic, and rheumatologic1 (0.0)0 (0.0)0.0 (−0.1 to 0.1)1 (0.0)0 (0.0)0.0 (−0.1 to 0.2)
 Child abuse0 (0.0)0 (0.0)1 (0.0)0 (0.0)0.0 (−0.1 to 0.2)
 Circulatory and cardiovascular disease96 (3.0)27 (1.2)1.8 (1.0 to 2.5)a114 (4.8)69 (4.3)0.6 (−0.8 to 1.9)
 Eye disease1 (0.0)0 (0.0)0.0 (−0.1 to 0.1)1 (0.0)0 (0.0)0.0 (−0.1 to 0.2)
 Endocrine, metabolic, and nutritional disease47 (1.5)35 (1.5)−0.1 (−0.8 to 0.6)52 (2.2)25 (1.5)0.7 (−0.2 to 1.5)
 ENT, dental, and mouth disease78 (2.4)34 (1.5)0.9 (0.1 to 1.7)a50 (2.1)5 (0.3)1.8 (1.1 to 2.5)a
 Fluid and electrolyte disorders22 (0.7)15 (0.7)0.0 (−0.4 to 0.5)31 (1.3)19 (1.2)0.1 (−0.6 to 0.9)
 Gastrointestinal disease12 (0.4)2 (0.1)0.3 (0.0 to 0.6)6 (0.3)2 (0.1)0.1 (−0.2 to 0.4)
 Genital and reproductive disease0 (0.0)1 (0.0)0.0 (−0.2 to 0.1)0 (0.0)0 (0.0)
 Hematologic disease13 (0.4)7 (0.3)0.1 (−0.3 to 0.4)3 (0.1)1 (0.1)0.1 (−0.2 to 0.3)
 Musculoskeletal and connective-tissue disease1 (0.0)0 (0.0)0.0 (−0.1 to 0.1)1 (0.0)2 (0.1)−0.1 (−0.3 to 0.2)
 Neoplastic disease (cancer, not benign neoplasms)0 (0.0)0 (0.0)0 (0.0)1 (0.1)−0.1 (−0.2 to 0.1)
 Neurologic disease100 (3.1)55 (2.4)0.7 (−0.2 to 1.6)132 (5.6)55 (3.4)2.2 (0.9 to 3.5)a
 Psychiatric, behavioral, and substance abuse1 (0.0)0 (0.0)0.0 (−0.1 to 0.1)0 (0.0)1 (0.1)0.0 (−0.2 to 0.1)
 Respiratory disease433 (13.4)224 (9.9)3.5 (1.8 to 5.2)a397 (16.8)259 (16.0)0.8 (−1.6 to 3.2)
 Skin, dermatologic, and soft-tissue disease0 (0.0)0 (0.0)0 (0.0)0 (0.0)
 Systemic states53 (1.6)46 (2.0)−0.4 (−1.2 to 0.4)49 (2.1)46 (2.8)−0.8 (−1.8 to 0.3)
 Toxicological emergencies0 (0.0)0 (0.0)2 (0.1)0 (0.0)0.1 (−0.1 to 0.3)
 Trauma2 (0.1)0 (0.0)0.1 (−0.1 to 0.2)7 (0.3)0 (0.0)0.3 (0.0 to 0.6)a
 Urinary tract disease16 (0.5)9 (0.4)0.1 (−0.3 to 0.5)10 (0.4)1 (0.1)0.4 (0.0 to 0.7)a
 Other365 (11.3)241 (10.6)0.7 (−1.1 to 2.4)35 (1.5)14 (0.9)0.6 (−0.1 to 1.3)
  • Because patients may have >1 high-acuity diagnosis, summed numbers of individual diagnoses do not equal total patients with high-acuity diagnoses. ENT, ear, nose, and throat; —, not applicable.

  • a 95% CIs do not cross 0.