TABLE 2

MRI Findings Among Confirmed Pediatric AFM Cases, United States, 2015–2017

201520162017Total
No. Patients (%)No. Patients (%)No. Patients (%)No. Patients (%)
MRI of spinal cord performedn = 18n = 143n = 32n = 193
 >1 region imaged16 (89)125 (87)28 (88)169 (88)
 Cervical cord imaged16 (89)133 (93)30 (94)179 (93)
  Cervical cord involvement11 (69)108 (81)25 (83)144 (80)
 Thoracic cord imaged15 (83)126 (88)28 (88)169 (88)
  Thoracic cord involvement10 (67)77 (61)18 (64)105 (62)
 Lumbar cord imaged15 (83)97 (68)25 (78)137 (71)
  Conus-cauda equina involvement8 (53)41 (42)6 (24)55 (40)
  Ventral nerve enhancement3 out of 11 (27)a18 out of 81 (22)a4 out of 11 (36)a25 out of 103 (24)a
MRI of brain performedn = 15n = 134n = 29n = 178
 Cranial nerve lesionsb2 (14)6 (5)1 (4)9 (6)
 Cerebral lesionsc6 (40)15 (12)8 (29)29 (17)
 Cerebellar lesionsd2 (14)12 (10)2 (8)16 (10)
 Brainstem lesionse7 (47)46 (36)12 (43)65 (38)
  Pontine lesions2 (29)29 (63)8 (67)39 (60)
  Medulla lesions7 (100)29 (63)7 (58)43 (66)
  Midbrain lesions1 (14)9 (20)4 (33)14 (22)
  • a Denominator is the number of patients reported having lumbosacral MRI performed, gadolinium administered, and a result available.

  • b Overall, 163 patients had a result available (2015, n = 15; 2016, n = 125; 2017, n = 24).

  • c Overall, 170 patients had a result available (2015, n = 15; 2016, n = 127; 2017, n = 29).

  • d Overall, 163 patients had a result available (2015, n = 14; 2016, n = 124; 2017, n = 25).

  • e Overall, 171 patients had a result available (2015, n = 15; 2016, n = 128; 2017, n = 28).