TABLE 1

SVR Cohort Main Outcomes at 6 Years Compared With Normative Sample

Instrument and DomainSVR Cohort Mean (SD)Abnormal (>1 SD) From Normative Mean (%)aAbnormal (>2 SD) From Normative Mean (%)bNormative Sample Mean (SD)Pc
Vineland-II
 Communication104.3 (18.6)24/222 (10.8)10/222 (4.5)100 (15)<.001
 Daily living skills102.3 (21.8)17/215 (7.9)15/215 (7.0)100 (15).035
 Socialization104.6 (19.5)17/182 (9.3)6/182 (3.3)100 (15)<.001
 Motor skills90.3 (17.8)49/215 (22.8)24/215 (11.2)100 (15)<.001
 Adaptive behavior composite101.1 (19.9)26/171 (15.2)10/171 (5.8)100 (15).218
BASC-2
 Internalizing behavior48.2 (9.9)11/245 (4.5)8/245 (3.3)50 (10)<.001
 Externalizing behavior49.4 (10.1)18/244 (7.4)10/244 (4.1)50 (10).040
 Behavior symptoms index50 (10)24/244 (9.8)10/244 (4.1)50 (10).318
 Adaptive skills composite47.3 (11.8)54/244 (22.1)16/244 (6.6)50 (10).001
PedsQL generic module
 Physical function70.6 (23.2)55/248 (22.2)26/248 (10.5)80.4 (20.8)<.001
 Emotional function77.0 (18.2)33/248 (13.3)19/248 (7.7)80.1 (15.9).007
 Social function76.1 (19.0)62/248 (25.0)5/248 (2.0)80.6 (20.4)<.001
 School function70.1 (20.1)57/247 (23.1)12/247 (4.9)77.4 (19.5)<.001
 Psychosocial health74.4 (15.6)59/248 (23.8)12/248 (4.8)79.4 (15.3)<.001
 Total score73.1 (16.7)57/248 (23.0)19/248 (7.7)79.7 (15.9)<.001
CHQ-PF50
 Physical summary T-score43.1 (12.3)53/248 (21.4)38/248 (15.3)53.1 (10.4)<.001
 Psychosocial summary T-score51.7 (8.7)38/248 (15.3)16/248 (6.5)52.5 (7.6).156
FSII(R)
 Total score92.4 (9.4)30/249 (12.0)49/249 (19.7)97.7 (4.5)<.001
  • a For the normative sample, 15.9% would be expected to score 1 SD below the mean.

  • b For the normative sample, 2.3% would be expected to score 2 SD below the mean.

  • c The distribution of scores for the SVR cohort was compared with the distribution of scores for the normative sample