TABLE 4

Test Characteristics of Aggregate Urinalysis for Diagnosing UTI, Stratified by Bacteremia Status and Age

Sensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)LR+ (95% CI)LR− (95% CI)
Identification of any UTIa (N = 289)
 Entire population, n = 41470.94 (0.91–0.97)0.91 (0.90–0.91)0.43 (0.39–0.47)1.00 (0.99–1.00)10.01 (9.04–11.08)0.06 (0.04–0.10)
 Infants ≤28 d, n = 12960.97 (0.92–0.99)0.90 (0.88–0.91)0.50 (0.43–0.56)1.00 (0.99–1.00)9.30 (7.84–11.03)0.04 (0.01–0.09)
 Infants 29–60 d, n = 28510.93 (0.88–0.96)0.91 (0.90–0.92)0.39 (0.34–0.44)1.00 (0.99–1.00)10.29 (9.06–11.69)0.08 (0.05–0.14)
Identification of UTIs with bacteremiaa (N = 27)
 Entire population, n = 38851.00 (0.87–1.00)0.91 (0.90–0.91)0.07 (0.05–0.10)1.00 (1.00–1.00)10.60 (9.61–11.69)0.00b
 Infants ≤28 d, n = 11861.00 (0.77–1.00)0.90 (0.88–0.91)0.10 (0.06–0.17)1.00 (1.00–1.00)9.61 (8.12–11.36)0.00b
 Infants 29–60 d, n = 26991.00 (0.75–1.00)0.91 (0.90–0.92)0.05 (0.03–0.09)1.00 (1.00–1.00)11.10 (9.84–12.52)0.00b
Identification of UTIs without bacteremiaa (N = 262)
 Entire population, n = 41200.94 (0.90–0.96)0.91 (0.90–0.91)0.40 (0.36–0.44)1.00 (0.99–1.00)9.95 (8.98–11.03)0.07 (0.04–0.11)
 Infants ≤28 d, n = 12820.96 (0.91–0.99)0.90 (0.88–0.91)0.46 (0.40–0.53)1.00 (0.99–1.00)9.26 (7.80–10.99)0.04 (0.02–0.11)
 Infants 29–60 d, n = 28380.92 (0.87–0.96)0.91 (0.90–0.92)0.37 (0.32–0.42)1.00 (0.99–1.00)10.22 (8.99–11.63)0.09 (0.05–0.15)
  • LR+, positive likelihood ratio; LR−, negative likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.

  • a Positive urinalysis results were defined by the presence of any LE or nitrite or pyuria.

  • b LR− does not have a CI because of a sensitivity of 1.00.