TABLE 2

Temporal Association of E-cigarette Use and Covariates at Wave 1 With Marijuana Use at Wave 2 Among Baseline Marijuana Never Users, PATH Study, 2013–2015

Marijuana Never Users at Wave 1Marijuana P12M Use at Wave 2Marijuana Heavy Use at Wave 2
nnWeighted % (95% CI)aORanWeighted % (95% CI)aORa
Total10 3648978.7 (8.1–9.3)2862.8 (2.4–3.2)
E-cigarette ever use
 No98207597.7 (7.1–8.4)Reference2452.5 (2.2–3.0)Reference
 Yes51113726.6 (22.6–31.0)1.9 (1.4–2.5)***417.9 (5.6–10.9)1.3 (0.8–2.1)b
Age, y
 12–1459013736.2 (5.6–6.9)Reference1282.2 (1.8–2.7)Reference
 15–17446352411.8 (10.7–13.0)1.4 (1.2–1.7)***1583.6 (3–4.4.0)1.1 (0.8–1.6)
Male52984318.2 (7.5–9.1)Reference1182.2 (1.8–2.8)Reference
Female50664669.1 (8.3–10.1)1.2 (1–1.4)*1683.4 (2.9–4.0)1.6 (1.2–2.2)**
Race and/or ethnicity
 NH white50794188.5 (7.6–9.4)Reference1472.9 (2.5–3.5)Reference
 NH African American141815611.2 (9.4–13.4)1.8 (1.3–2.4)***392.9 (2.0–4.2)1.2 (0.8–2.0)
 Hispanic29322408.3 (7.3–9.3)1.0 (0.8–1.2)792.8 (2.2–3.6)1.0 (0.7–1.5)
 NH others935837.1 (5.5–9.1)0.9 (0.7–1.3)211.9 (1.1–3.3)0.7 (0.4–1.2)
Grade performance
 A28071615.6 (4.7–6.6)Reference471.7 (1.2–2.3)Reference
 B45283848.8 (8.0–9.6)1.4 (1.1–1.7)**1132.7 (2.2–3.3)1.4 (0.9–2.3)
 C or below298634911.9 (10.5–13.4)1.8 (1.4–2.3)***1254.2 (3.5–5.1)2.2 (1.4–3.6)**
Parental education
 Less than high school20971909.3 (8.2–10.6)Reference612.9 (2.2–3.7)Reference
 High school graduate18741749.2 (8.0–10.6)0.9 (0.7–1.1)603.3 (2.6–4.3)1.1 (0.8–1.6)
 Some college32563029.3 (8.2–10.4)0.9 (0.7–1.1)973 (2.4–3.7.0)0.9 (0.6–1.3)
 Bachelor’s degree or greater30682217.4 (6.4–8.5)0.9 (0.7–1.1)642.3 (1.7–3.0)0.9 (0.6–1.3)
Region
 Northeast14821419.9 (8.2–11.8)Reference503.5 (2.5–5.0)Reference
 South23142139.1 (8.0–10.4)0.8 (0.7–1.1)652.8 (2.2–3.6)0.7 (0.5–1.2)
 Midwest39323188.0 (7.0–9.1)0.7 (0.5–0.9)*1002.5 (2.0–3.1)0.6 (0.4–1.0)
 West26362258.5 (7.2–10.0)0.9 (0.7–1.2)712.8 (2.0–4.0)0.8 (0.5–1.4)
Cigarette ever use
 No97327327.5 (6.9–8.2)Reference2272.4 (2.1–2.8)Reference
 Yes61916326.5 (22.6–30.9)2.0 (1.5–2.7)***599.4 (7.1–12.3)2.1 (1.4–3.2)***
Alcohol ever use
 No72263925.3 (4.8–5.9)Reference1081.6 (1.2–1.9)Reference
 Yes308849916.2 (14.8–17.8)2.3 (1.9–2.8)***1775.6 (4.8–6.6)2.4 (1.8–3.3)***
Nonmedical use of prescription drugs
 No94677848.3 (7.7–9.0)Reference2472.6 (2.3–3.0)Reference
 Yes74310113.1 (10.4–16.4)1.2 (0.9–1.5)375.0 (3.4–7.3)1.2 (0.8–1.8)
Other illicit drug ever use
 No10 2558838.7 (8.0–9.3)Reference2822.8 (2.4–3.2)Reference
 Yes29517.4 (7.5–35.1)1.0 (0.3–3.4)312.0 (4.3–29)2.4 (0.7–8.7)
Sensation seekingc1.6 (1.5–1.7)***1.7 (1.5–2)***
  • —, not applicable.

  • a aOR was calculated in the multivariable logistic regression, in which the explanatory variables included all listed variables (demographics, substance ever use, and sensation seeking) at wave 1.

  • b There were significant interactions between age and e-cigarette use. See Table 3.

  • c aOR corresponds to 1 U increase in the risk of sensation seeking (5-point scale).

  • * P < .05;

  • ** P < .01;

  • *** P < .001.