TABLE 4

Rotavirus-Coded Hospitalization Rates and Rate Reductions by Season, Among Unvaccinated Children After RV5 or RV1 Introductiona

Study PeriodHospitalization Rate, n/10 000 PYRate Reduction (95% CI), %
AllNortheastMidwestSouthWestAllNortheastMidwestSouthWest
2001–2006b2416253113refrefrefrefref
2007–200812412111950 (36 to 62)76 (–13 to 95)52 (24 to 70)66 (50 to 78)−53 (–166 to 12)
2008–20092312292572 (–17 to 18)24 (–86 to 69)−16 (–52 to 12)19 (–4 to 37)41 (–40 to 76)
2009–20105737577 (65 to 85)57 (–43 to 87)89 (69 to 96)76 (58 to 86)59 (–33 to 87)
2010–201118827171325 (4 to 41)50 (–23 to 79)−7 (–52 to 25)46 (20 to 64)1 (–120 to 55)
  • CI, confidence interval; PY, person-year; ref, reference group.

  • a Data for each postvaccine study period were averaged among unvaccinated children who were age-eligible for the vaccine: those aged 3–17 mo by July 1, 2007, and those aged 3–23 mo by July 1, 2008; July 1, 2009; and July 1, 2010. Age groups were standardized by birth quarter. Rate reductions for diarrhea-associated emergency department and outpatient visits are provided in SupplementaryInformation Table 8. Children who were from states with universal vaccination programs were excluded.

  • b Average annual hospitalization rate for 2001–2006 among children under 2 y of age during the July–June study period.