TABLE 1

Disease Categories Addressed in 559 Pediatric RCTs

Condition CategoryPediatric Trials, n (%)
Allergy and atopy18 (3.2)
Anesthesia, critical care, and surgery34 (6.1)
Cardiovascular and circulatory diseases18 (3.2)
Chronic respiratory disease25 (4.5)
Common childhood vaccines135 (24.2)
Diabetes and endocrine diseases40 (7.2)
Diarrheal illnesses, lower respiratory infections, meningitis, and other common infectious diseases45 (8.1)
Digestive and liver disease13 (2.3)
Genetic and metabolic disease9 (1.6)
HIV/AIDS and tuberculosis9 (1.6)
Mental and behavioral disorders63 (11.3)
Musculoskeletal disorders6 (1.1)
Neglected tropical diseases26 (4.7)
Neonatal and infant medicine56 (10.0)
Neoplasm8 (1.4)
Neurologic disorders8 (1.4)
Nutrition and nutritional deficiencies27 (4.8)
Unintentional injuries6 (1.1)
Other13 (2.3)