TABLE 3

Primary Outcome: NIPS Score During Circumcision

EMLA (n = 10)EMLA + Sucrose (n = 20)EMLA + Sucrose + DPNB (n = 20)EMLA + Sucrose + RB (n = 20)
Mean (SD)Mean (SD)PMean (SD)PMean (SD)P
Overall5.50 (0.53)3.10 (1.33)<.001a3 (1.33)<.001a2.45 (1.27)<.001a
Stage 15.90 (0.31)2.85 (2.08)<.001a2.80 (2.41)<.001a2.70 (2.45)<.001a
Stage 25.30 (1.48)1.55 (1.96)<.001a1.40 (2.06)<.001a1.40 (1.85)<.001a
Stage 364.70 (1.30).0604.55 (2.06).031a4.50 (1.64)<.001a
Stage 45.80 (0.632)4.30 (2.10).041a4.40 (1.73).020a2.25 (1.65)<.001a; .009b; .002b
Stage 53.80 (1.93)1.55 (1.53).001a1.60 (1.60).001a1.20 (1.29)<.001a
Stage 65.80 (0.632)3.50 (2.33).002a3.35 (2.32).001a1.95 (1.88)<.001a
  • a Statistically significant difference between the current intervention group and the control group (EMLA).

  • b Statistically significant difference between the current intervention group and another intervention group (EMLA + sucrose and EMLA + sucrose + DPNB, respectively).