TABLE 3

Selected Clinical Effects Associate With Laundry or Dishwasher Detergent Exposures Among Children Younger Than 6 Years by Types of Detergent, NPDS 2013–2014

Clinical EffectsDishwasherLaundryClinical Effects Total, n (%)a
Nonpacket, n (%)a)Packet, n (%)aTotal, n (%)aNonpacket, n (%)aPacket, n (%)aTotal, n (%)a
Cardiac effects
 Tachycardia8 (0.1)1 (0.0)9 (0.0)19 (0.1)144 (0.7)163 (0.5)172 (0.3)
 Chest pain (including noncardiac)1 (0.0)6 (0.0)7 (0.0)7 (0.0)
 Bradycardia4 (0.0)4 (0.0)4 (0.0)
 Cardiac arrest2 (0.0)2 (0.0)2 (0.0)
 Dysrhythmia (other)1 (0.0)1 (0.0)1 (0.0)
Dermal effects
 Erythema/flushed51 (0.4)50 (0.3)101 (0.4)129 (1.0)371 (1.7)500 (1.4)601 (1.0)
 Edema10 (0.1)11 (0.1)21 (0.1)118 (0.9)363 (1.6)481 (1.4)502 (0.8)
 Rash36 (0.3)22 (0.1)58 (0.2)79 (0.6)280 (1.3)359 (1.0)417 (0.7)
 Dermal—irritation/pain27 (0.2)42 (0.3)69 (0.3)86 (0.7)243 (1.1)329 (0.9)398 (0.6)
 Burns second—third degree1 (0.0)1 (0.0)3 (0.0)9 (0.0)12 (0.0)13 (0.0)
 Burns (superficial)4 (0.0)7 (0.0)11 (0.0)10 (0.1)55 (0.2)65 (0.2)76 (0.1)
Gastrointestinal effects
 Vomiting1725 (14.4)3184 (21.1)4909 (18.1)2704 (20.6)10 504 (47.6)13 208 (37.5)18 117 (29.1)
 Nausea120 (1.0)158 (1.0)278 (1.0)223 (1.7)874 (4.0)1097 (3.1)1375 (2.2)
 Oral irritation243 (2.0)281 (1.9)524 (1.9)240 (1.8)611 (2.8)851 (2.4)1375 (2.2)
 Throat irritation29 (0.2)29 (0.2)58 (0.2)108 (0.8)424 (1.9)532 (1.5)590 (0.9)
 Diarrhea28 (0.2)30 (0.2)58 (0.2)74 (0.6)367 (1.7)441 (1.3)499 (0.8)
 Abdominal pain24 (0.2)19 (0.1)43 (0.2)55 (0.4)160 (0.7)215 (0.6)258 (0.4)
 Oral burns (including lips)3 (0.0)5 (0.0)8 (0.0)6 (0.0)40 (0.2)46 (0.1)54 (0.1)
 Dysphagia3 (0.0)2 (0.0)5 (0.0)8 (0.1)39 (0.2)47 (0.1)52 (0.1)
 Oropharyngeal edema3 (0.0)1 (0.0)4 (0.0)9 (0.1)31 (0.1)40 (0.1)44 (0.1)
 Esophageal injury2 (0.0)1 (0.0)3 (0.0)2 (0.0)33 (0.1)35 (0.1)38 (0.1)
 Hematemesis3 (0.0)1 (0.0)4 (0.0)5 (0.0)16 (0.1)21 (0.1)25 (0.0)
 Esophageal stricture1 (0.0)1 (0.0)1 (0.0)1 (0.0)2 (0.0)
 Melena2 (0.0)2 (0.0)2 (0.0)
Hematologic/hepatic effects
 Other coagulopathy3 (0.0)3 (0.0)3 (0.0)
 Other LFT abnormality3 (0.0)3 (0.0)3 (0.0)
Miscellaneous effects
 Excess secretions18 (0.2)28 (0.2)46 (0.2)40 (0.3)325 (1.5)365 (1.0)411 (0.7)
 Fever/hyperthermia9 (0.1)17 (0.1)26 (0.1)23 (0.2)114 (0.5)137 (0.4)163 (0.3)
 Acidosis1 (0.0)1 (0.0)6 (0.0)51 (0.2)57 (0.2)58 (0.1)
 Bleeding (other)7 (0.1)7 (0.0)14 (0.1)6 (0.0)8 (0.0)14 (0.0)28 (0.0)
 Pain (not dermal, GI, ocular)2 (0.0)1 (0.0)3 (0.0)11 (0.1)9 (0.0)20 (0.1)23 (0.0)
Neurologic effects
 Drowsiness/lethargy21 (0.2)28 (0.2)49 (0.2)211 (1.6)1504 (6.8)1715 (4.9)1764 (2.8)
 Agitated/irritable28 (0.2)32 (0.2)60 (0.2)53 (0.4)220 (1.0)273 (0.8)333 (0.5)
 Ataxia3 (0.0)16 (0.1)19 (0.1)19 (0.0)
 Coma17 (0.1)17 (0.0)17 (0.0)
 Seizure (single)1 (0.0)1 (0.0)4 (0.0)11 (0.0)15 (0.0)16 (0.0)
 Syncope3 (0.0)3 (0.0)3 (0.0)
Ocular effects
 Ocular—irritation/pain77 (0.6)71 (0.5)148 (0.5)895 (6.8)2437 (11.0)3332 (9.5)3480 (5.6)
 Red eye/conjunctivitis41 (0.3)29 (0.2)70 (0.3)521 (4.0)1547 (7.0)2068 (5.9)2138 (3.4)
 Lacrimation13 (0.1)10 (0.1)23 (0.1)107 (0.8)311 (1.4)418 (1.2)441 (0.7)
 Corneal abrasion2 (0.0)5 (0.0)7 (0.0)77 (0.6)293 (1.3)370 (1.1)377 (0.6)
 Burns15 (0.1)80 (0.4)95 (0.3)95 (0.2)
 Photophobia1 (0.0)1 (0.0)10 (0.1)49 (0.2)59 (0.2)60 (0.1)
 Papilledema1 (0.0)1 (0.0)1 (0.0)8 (0.0)9 (0.0)10 (0.0)
Respiratory effects
 Cough/choke488 (4.1)891 (5.9)1379 (5.1)770 (5.9)3004 (13.6)3774 (10.7)5153 (8.3)
 Dyspnea11 (0.1)7 (0.0)18 (0.1)33 (0.3)245 (1.1)278 (0.8)296 (0.5)
 Bronchospasm3 (0.0)2 (0.0)5 (0.0)15 (0.1)153 (0.7)168 (0.5)173 (0.3)
 Radiograph findings (+)2 (0.0)2 (0.0)13 (0.1)131 (0.6)144 (0.4)146 (0.2)
 Hyperventilation/tachypnea3 (0.0)3 (0.0)9 (0.1)95 (0.4)104 (0.3)107 (0.2)
 Respiratory depression5 (0.0)67 (0.3)72 (0.2)72 (0.1)
 Pneumonitis1 (0.0)1 (0.0)3 (0.0)32 (0.1)35 (0.1)36 (0.1)
 Cyanosis3 (0.0)3 (0.0)1 (0.0)17 (0.1)18 (0.1)21 (0.0)
 Respiratory arrest6 (0.0)6 (0.0)6 (0.0)
 Pulmonary edema4 (0.0)4 (0.0)4 (0.0)
Total exposures (row %)b11 989 (19.3)15 077 (24.2)27 066 (43.5)13 124 (21.1)22 064 (35.4)35 188 (56.5)62 254 (100.0)
  • GI, gastrointestinal; LFT, liver function test; —, no clinical effect.

  • a Column percentages were calculated by using the total number of exposures for each detergent category as the denominator. Percentages will not sum to 100.0% because an exposed child may or may not experience 1 or more clinical effects.

  • b Row percentages.