TABLE1

Full Influenza Vaccination Recommendations and Number of Doses Needed to be Fully Vaccinated, National Immunization Survey (NIS), Provider-Report, United States, 2002–2003 Through 2011–2012 Influenza Seasons

Influenza SeasonRecommendationsaChildren Who Needed 2 Doses, % ± 95% CIb
2002–2003“Among previously unvaccinated children aged <9 years, two doses administered >1 months apart are recommended for satisfactory antibody responses.“299.2 ± 0.2
2003–2004“Among previously unvaccinated children aged <9 years, two doses administered >1 month apart are recommended for satisfactory antibody responses.”1496.5 ± 0.4
2004–2005“Among previously unvaccinated children aged <9 years, 2 doses administered >1 month apart are recommended for satisfactory antibody responses. If possible, the second dose should be administered before December. If a child aged <9 years receiving vaccine for the first time does not receive a second dose of vaccine within the same season, only 1 dose of vaccine should be administered the following season. Two doses are not required at that time.”392.0 ± 0.6
2005–2006“Among previously unvaccinated children aged <9 years, 2 doses administered >1 month apart are recommended for satisfactory antibody responses. If possible, the second dose should be administered before December. If a child aged <9 years receiving vaccine for the first time does not receive a second dose of vaccine within the same season, only 1 dose of vaccine should be administered the following season. Two doses are not required at that time.”1581.5 ± 0.8
2006–2007“Among previously unvaccinated children aged 6 months–<9 years, 2 doses of inactivated vaccine administered >1 month apart are recommended for eliciting satisfactory antibody responses. If possible, the second dose should be administered before the onset of influenza season. If a child aged 6 months–<9 years receiving influenza vaccine for the first time does not receive a second dose of vaccine within the same season, only 1 dose of vaccine should be administered the following season. Two doses are not required at that time.”1681.0 ± 1.0
2007–2008“ACIP recommends 2 vaccine doses for children aged 6 months–8 years who received an influenza vaccine (either TIV or LAIV) for the first time in the previous season but who did not receive the recommended second dose of vaccine within the same season. ACIP recommendations are now harmonized with regard to this issue with those of AAP. This recommendation represents a change from the 2006 recommendations, in which children aged 6 months–8 years who received only 1 dose of vaccine in their first year of vaccination were recommended to receive only a single dose in the following season. ACIP does not recommend that a child receive influenza vaccine for the first time in the spring with the intent of providing a priming dose for the following season. Children recommended for vaccination who are in their third or more year of being vaccinated and who received only 1 dose in each of their first 2 years of being vaccinated should continue receiving a single annual dose.”1788.7 ± 0.6
2008–2009“All children aged 6 months–8 years who have not received vaccination against influenza previously should receive 2 doses of vaccine the first influenza season that they are vaccinated. The second dose should be administered 4 or more weeks after the initial dose. For example, children aged 6 months–8 years who were vaccinated for the first time during the 2007–08 influenza season but only received 1 dose during that season should receive 2 doses of the 2008–09 influenza vaccine. All other children aged 6 months–8 years who have previously received 1 or more doses of influenza vaccine at any time should receive 1 dose of the 2008–09 influenza vaccine. Children aged 6 months–8 years who only received a single vaccination during a season before 2007–08 should receive 1 dose of the 2008–09 influenza vaccine.”1887.6 ± 0.8
2009–2010“All children aged 6 months–8 years who have not received vaccination against influenza previously should receive 2 doses of vaccine the first influenza season that they are vaccinated. The second dose should be administered 4 or more weeks after the initial dose. When only 1 dose is administered to children aged 6 months–8 years during their first year of vaccination, 2 doses should be administered in the following season. However, 2 doses should only be administered in the first season of vaccination, or in the season that immediately follows if only 1 dose is administered in the first season. For example, children aged 6 months–8 years who were vaccinated for the first time with the 2008–09 influenza vaccine but received only 1 dose should receive 2 doses of the 2009–10 influenza vaccine. All other children aged 6 months–8 years who have previously received 1 or more doses of influenza vaccine at any time should receive 1 dose of the 2009–10 influenza vaccine. Children aged 6 months–8 years who received only a single vaccination during a season before 2007–08 should receive 1 dose of the 2009–10 influenza vaccine.”584.4 ± 0.8
2010–2011“All children aged 6 months–8 years who receive a seasonal influenza vaccine for the first time should be administered 2 doses. Children aged 6 months–8 years who received a seasonal vaccine for the first time during 2009–2010 but who received only 1 dose should receive 2 doses, rather than 1, during 2010–2011. In addition, for the 2010–11 influenza season, children aged 6 months–8 years who did not receive at least 1 dose of an influenza A (H1N1) 2009 monovalent vaccine should receive 2 doses of a 2010–11 seasonal influenza vaccine, regardless of previous influenza vaccination history. Children aged 6 months–8 years for whom the previous 2009–10 seasonal or influenza A (H1N1) 2009 monovalent vaccine history cannot be determined should receive 2 doses of a 2010–11 seasonal influenza vaccine.”990.3 ± 0.6
2011–2012“Vaccination providers should note that, in previous seasons, children aged 6 months through 8 years who received only 1 dose of influenza vaccine in their first year of vaccination required 2 doses the following season. However, because the 2011–12 vaccine strains are unchanged from the 2010–11 season, children in this age group who received at least 1 dose of the 2010–11 seasonal vaccine will require only 1 dose of the 2011–12 vaccine. Children in this age group who did not receive at least 1 dose of the 2010–11 seasonal influenza vaccine, or for whom it is not certain whether the 2010–11 seasonal vaccine was received, should receive 2 doses of the 2011–12 seasonal influenza vaccine.”1070.1 ± 1.2
  • CI, confidence interval.

  • a Recommendations regarding which children required 2 doses versus 1 dose to be fully vaccinated against influenza, as published in the annual “Prevention and Control of Influenza: Recommendations of the Advisory Committee on Immunization Practices (ACIP),” published in Morbidity and Mortality Weekly Report.

  • b Aged 6 to 23 months.