TABLE 2

Factors Associated With (A) Additional PCV13 Serotype Colonization and (B) Non-PCV13 Serotype Colonization in Our Study Population From 2001 to 2014

Additional PCV13 Serotype ColonizationNon-PCV13 Serotype Colonization
Adjusted OR (95% CI)PAdjusted OR (95% CI)P
Age group (mo).0006<.0001
 <62.43 (1.26–4.68)1.73 (0.99–2.17)
 6–<122.74 (1.64–4.59)2.46 (1.45–2.70)
 12–<242.30 (1.41–3.73)2.26 (1.43–2.55)
 24–<601.49 (0.95–2.34)1.70 (1.15–1.90)
 60–<841.01.0
Female0.95 (0.73–1.23).710.97 (0.85–1.11).65
Child care (h)<.002<.0001
 0–<40.55 (0.40–0.75)0.46 (0.39–0.54)
 4–100.67 (0.43–1.06)0.75 (0.60–0.94)
 11–200.71 (0.44–1.14)0.90 (0.72–1.13)
 >201.01.0
Smoker in household1.46 (1.10–1.94).00960.86 (0.73–1.02).08
Presence of respiratory tract infection at time of swaba1.37 (1.05–1.79).0191.47 (1.28–1.70)<.0001
Vaccination UTD status<.0001<.0001
 UTD for PCV71.16 (0.82–1.64)1.29 (1.06–1.58)
 UTD for PCV130.48 (0.31–0.75)1.66 (1.34–2.06)
 Not UTD for either1.01.0
Recent antibiotic use in past 6 mo.034<.0001
 <2 wk ago1.11 (0.69–1.78)0.28 (0.19–0.42)
 2–<4 wk ago1.63 (1.06–2.52)0.40 (0.28–0.56)
 4–<8 wk ago1.01 (0.62–1.66)0.66 (0.50–0.87)
 8 wk–≤6 mo ago1.58 (1.13–2.21)0.46 (0.23–0.93)
 None1.01.0
  • a Respiratory tract infection is defined on the basis of symptoms or clinician diagnosis, including upper respiratory tract symptoms (rhinorrhea, congestion, sore throat), acute otitis media, otitis media with effusion, bronchiolitis, pharyngitis, upper respiratory tract infection, viral syndrome, and croup.