TABLE 5

Clinical Characteristics as a Function of Auditory Toxicity in the Subgroup of Neonates With TSB ≥25 mg/dL (N = 30)

Neonates Without Auditory Toxicity (n = 23)Neonates With Auditory Toxicity (n = 7)P
GA, wksa37.6 (1.5)37.4 (0.53).84b
Birth weight, ga2768 (478)2715 (486).79b
Sex, n (% male)11 (48)5 (71).39c
Mode of delivery, n (% cesarean delivery)4 (17)0 (0).54c
Serum albumin (g/dL)a3.6 (0.7)3.9 (0.6).17b
Bilirubin binding capacity (mg/dL)a31.8 (6.7)34.5 (5.5).17b
Sepsis, n (%)1 (4)2 (28).12c
Asphyxia (apgar score <3 at 5 min), n (%)0 (0)0 (0)1.00c
Hemolytic disorders, n (%)6 (23)2 (28).69c
Polycythemia, n (%)1 (4)0 (0).99c
Breast milk feeding, n (%)22 (96)7 (100).99c
Clinical risk factor, n (%)7 (30)4 (57).37c
ET, n (%)18 (78)7 (100).30c
  • Clinical risk factors: hemolysis, asphyxia, hypoxia (Pao2 <45 mm Hg), acidosis (pH <7.25), or albumin <3 g/dL.

  • a Mean (SD).

  • b Mann–Whitney U test.

  • c Fisher’s exact test.