TABLE 1

Association of Supplements with Transaminitis

Case No.Age, SexElevated Liver Transaminase(s), IU/LCumulative Dose of Isotretinoin at Time of Elevated ALT or AST, mg/kgLikely Cause of Elevated Liver Transaminase(s)
Supplements most likely caused transaminitis
117, boyALT 57 13.1 Protein supplements
AST 37
215, boyALT 55 94.5 Protein and muscle-building supplements and energy drinks
AST 49
316, boyALT 50 N/AInitially: protein supplements, creatine supplements, minocycline, and/or viral illness
AST 29 Later causes: protein and/or creatine supplements
417, boyALT 40 N/AGreen tea supplements
AST 140
516, girlALT 27 N/AProtein supplements
AST 74
615, boyALT 36 92 Initially: protein supplements
AST 187 Later causes: protein supplements and/or illness
Supplements possibly caused or contributed to transaminitis
716, boyALT 34 114.4 Creatine supplements and/or isotretinoin
AST 65
816, boyALT 56 40.7 Protein supplementation and/or isotretinoin
AST 41
  • N/A, not applicable.