TABLE 1

Comparison of Spontaneous DA Closure Time Among Different BW and GA Groups (Statistical Significance P < .05)

N = 280Time to Ductal Closure (d), Median (95% CI)Pairwise Comparison Between the Groups, P, Mantel-Cox Log Rank TestAdjusted P Value for Multiple Comparisons (Bonferroni Correction)
IQR [Q1, Q3]
SE of the Median (Kaplan-Meier)
≤750 ga48 (9–87)
[8, 94].700b>.999b
20.058c.347c
<.001d<.001d
751–1000 gb22 (6–38).700a>.999a
[7, NA]
8.042c.255c
<.001d<.001d
1001–1250 gc9 (6–12).058a.347a
[3, 44].042b.255b
2
<.001d.002d
1251–1500 gd8 (7–9)<.001a<.001a
[3, 12]<.001b<.001b
1<.001c.002c
<26+0 GAe71 (51–91)
[18, NA].028f.169f
10<.001g<.001g
<.001h<.001h
26+0–27+6 GAf13 (0–34).028e.169e
[6, NA]
11.001g.003g
<.001h<.001h
28+0–29+6 GAg8 (7–9)<.001e<.001e
[5, 17].001f.003f
1
.027h.164h
>30 GAh9 (4–8)<.001e<.001e
[2, 11]<.001f<.001f
1.027g.164g
  • P value is a result of comparison of the BW and GA groups labeled a, b, c, d and e, f, g, h, respectively. NA, not applicable (because Q3 was outside of the inpatient stay); IQR, interquartile range; Q1, 25th percentile; Q3, 75th percentile.