TABLE 2

National Estimates of Medication Classes Most Commonly Implicated in Emergency Hospitalizations for Unsupervised Oral Prescription Medication Ingestions by Children Aged <6 Years: United States, 2007–2011

Medication ClassAnnual National Estimate of HospitalizationsProportion of ED Visits Resulting in Hospitalization, %
NumberPercentage(95% CI)
Opioid analgesics166617.6(13.9–21.2)36.5
Benzodiazepines96010.1(8.0–12.3)23.9
Sulfonylureas774a8.2(4.4–11.9)77.8
β-Blockers7608.0(5.8–10.2)32.1
Centrally acting antiadrenergicsb7598.0(5.5–10.5)53.5
Calcium channel blockersc7397.8(4.4–11.2)57.4
Atypical antipsychotics6296.6(4.8–8.4)36.7
SSRIs4574.8(2.6–7.0)22.3
Anticonvulsants4384.6(3.2–6.1)26.1
ACE inhibitorsc3884.1(2.8–5.3)28.0
Skeletal muscle relaxants2943.1(1.9–4.2)20.9
Amphetamine-related stimulants292a3.1(1.5–4.7)17.2
  • Estimates were based on data from the NEISS-CADES project, 2007–2011. ACE, angiotensin-converting enzyme; SSRI, selective serotonin reuptake inhibitor.

  • a Coefficient of variation >30%.

  • b Includes clonidine, guanfacine, and methyldopa.

  • c Three surveillance cases involving hospitalizations for unsupervised ingestion of calcium channel blocker/ACE inhibitor combination products are included in national estimates for both medication classes.