TABLE 3

National Estimates of Active Ingredients Most Commonly Implicated in Emergency Hospitalizations for Unsupervised Oral Prescription Medication Ingestions by Children Aged <6 Years: United States, 2007–2011

Active IngredientAnnual National Estimate of HospitalizationsProportion of ED Visits Resulting in Hospitalization, %
NumberPercentage(95% CI)
Buprenorphine7347.7(3.9–11.5)62.4
Clonidine7017.4(4.9–9.8)56.2
Glipizide386a4.1a(1.0–7.2)74.2
Clonazepam3683.9(2.3–5.5)24.0
Metoprolol3143.3(1.8–4.8)34.5
Lorazepam3093.3(1.7–4.8)38.4
Lisinopril2983.1(2.0–4.3)28.9
Amlodipine2953.1(1.3–4.9)51.4
Bupropion2652.8(1.5–4.1)56.2
Glyburide257a2.7(1.2–4.2)75.1
Hydrocodoneb252a2.7(1.4–3.9)30.5
Oxycodone2492.6(1.5–3.8)26.1
  • Estimates were based on data from the NEISS-CADES project, 2007–2011.

  • a Coefficient of variation >30%.

  • b Excludes 5 surveillance cases involving hospitalizations for unsupervised ingestion of antitussive combination products.