TABLE 2

One-Year Survival and Neonatal Morbidities Among Infants Born in 2013–2014, GA 22 to 26 Weeks

22 Weeks23 Weeks24 Weeks25 Weeks26 Weeks22–26 Weeks
One-year survival
 Survival, n312355976185
 % survival of all births (95% CI)5 (1–13)17 (9–27)41(31–52)65 (54–75)72 (62–80)44 (39–49)
 % survival of fetuses alive by admission to an obstetrical unit (95% CI)6 (1–18)22 (12–35)49 (37–61)80 (69–88)87 (79–94)55 (50–61)
 % survival of live-births (95% CI)18 (4–43)29 (16–45)56 (43–69)84 (74–92)90 (82–96)67 (61–73)
 % survival of infants admitted to NICU (95% CI)60 (15–95)35 (20–54)58 (45–71)86 (75–93)92 (83–97)74 (68–79)
Morbidities
 Early-onset sepsis,a n (% admitted to NICU)0 (0)1 (2.9)4 (6.7)3 (4.3)2 (2.4)10 (4.0)
 Late-onset sepsis,b n (% admitted to NICU)1 (20.0)8 (23.5)13 (21.7)27 (39.1)18 (21.7)67 (26.7)
 ICH, Papile grade 3–4, n (% of survivors)0 (0)0 (0)5 (14.3)6 (10.2)3 (3.9)14 (7.6)
 cPVL, n (% of survivors)0 (0)0 (0)0 (0)3 (5.1)7 (9.2)10 (5.4)
 ROP, stage 3–5, n (% of survivors)0 (0)4 (33.3)12 (34.3)11 (18.6)5 (6.6)32 (17.3)
 NEC, Bell stage 2–3, n (% of survivors)0 (0)2 (16.7)2 (5.7)5 (8.5)1 (1.3)10 (5.4)
 Severe BPD,c n (% of survivors)2 (66.7)7 (58.3)20 (57.1)20 (33.9)29 (38.2)78 (42.2)
 Major neonatal morbidity,d n (% of survivors)2 (66.7)9 (75.0)25 (71.4)32 (54.2)34 (44.7)102 (55.1)
  • a Microbiologically verified sepsis at <3 d of life.

  • b Microbiologically verified sepsis at 3 d of life or older.

  • c Need for positive pressure ventilation or at least 30% oxygen at 36 wk postmenstrual age.

  • d ICH Papile grade 3–4 or cystic.