TABLE 2

Outcomes After Immunization

BPDNo BPDOR (95% CI)P
All patients and all immunization eventsa
 Primary outcomes
  Respiratory decompensation within 72 hours of immunizationb26 (8)5 (5)1.47 (0.55–3.94).65
  Increased effective Fio2 ≥10% above previous 24-hour mean4 (1)0.58
  Increased respiratory support within 72 hours of immunization24 (7)5 (5)1.35 (0.50–3.64).65
 Secondary outcome
  Increased A/B/D events within 72 hours of immunization97 (29)23 (25)1.23 (0.73–2.08).51
Two-month immunization patients and eventsc
 Primary outcomes
  Respiratory decompensation within 72 hours of immunizationb16 (9)5 (7)1.37 (0.49–3.90).63
  Increased effective Fio2 ≥10% above previous 24-hour mean00
  Increased respiratory support within 72 hours of immunization16 (9)5 (7)1.37 (0.49–3.90).63
 Secondary outcome
  Increased A/B/D events within 72 hours of immunization64 (36)20 (27)1.53 (0.84–2.78).19
  • Data are presented as n (%) unless otherwise indicated. Odds ratios calculated when possible.

  • a In the BPD group there were 172 subjects with 337 immunization events; in the No BPD group there were 68 subjects with 93 immunization events.

  • b Respiratory decompensation within 72 hours of immunization is a composite score of increased effective Fio2 ≥10% above the previous 24-hour mean or increased respiratory support within 72 hours of immunization.

  • c In the BPD group there were 145 subjects with 179 immunization events; in the No BPD group there were 65 subjects with 75 immunization events.