TABLE 1

Summary of the Included Trials

StudyLocationTotal Trial Patients, NIncluded in the Systematic Review, NLost to Follow-Up, NAge, yDuration, moMetformin DoseOCP Type and DoseOutcomes
Al-Zubeidi 2015United States34341214–1861000 BIDNorethindrone1 mg, ethinyl estradiol 30 µgHirsutism
BMI
Lipid profile
Total testosterone
Side effects
Allen 2005United States3535412–2161000 BIDNorgestimate 0.25 mg, ethinyl estradiol 35 µgMenstrual regulation
Hirsutism
Acne
BMI
Lipid profile
Total testosterone
Hoeger 2008United States4321512–186850 BIDDesogestrel 0.15 mg, ethinyl estradiol 30 µgMenstrual regulation
Hirsutism
Dysglycemia
BMI
Lipid profile
Total testosterone
El Maghraby 2014Egypt119801515–2024850 BIDProgestin 15 mg, ethinyl estradiol 30 µgMenstrual regulation
Hirsutism
BMI
Lipid profile
Total testosterone
Side effects
Total23117036
  • BID, 2 times daily.