TABLE 3

Investigations and Diagnosis of Infection in NVP-FS and VP-FS Cases

NVP-FS (n = 921)VP-FS (n = 67)P
Tested (All Cases)Positive (All Tested)Tested (All Cases)Positive (All Tested)
n (%)319 (34.6)88 (27.6)27 (40.3)8 (29.6).82
Laboratory investigations, n (%)
 NPA92 (10.0)50 (54.3)8 (11.9)6 (75.0).13
 Stool culture44 (4.8)11 (25.0)5 (7.5)1 (20.0).81
 Urine culture218 (23.7)43 (19.7)19 (28.4)4 (21.1).89
 Blood culture221 (24.0)6 (2.7)14 (20.9)0 (0.0).86
Neurologic investigations,a n (%)41 (4.5)6 (9.0)
 EEG29 (3.1)8 (27.6)3 (4.5)1 (33.3).83
 CT or MRI brain28 (3.0)4 (14.3)4 (6.0)0 (0.0).70
Diagnosis of infection,b n
 Bacteraemia and/or sepsis30
 Gastroenteritis (viral)50
 Gastroenteritis (bacterial)61
 Respiratory infection495
 Urinary tract infection252
  • P = χ2 test comparing the proportion cases that tested with positive results in each FS group for each investigation. —, not applicable.

  • a Positive for neurologic investigations refers to an abnormality found on the investigation.

  • b Laboratory isolates in VP-FS group include 2 cases of E coli and 1 case of each of the following: rhinovirus; rhinovirus, respiratory syncytial virus, and adenovirus combination; enterovirus; human metapneumovirus; parainfluenza virus; and parechovirus.