TABLE 3

SMRs for Each Type of Outcome in Children With an Underlying Disease

Category of EventsWith Cardiovascular, Respiratory, or Metabolic Diseasea
ObservedExpectedSMRbCI 95%
With cardiovascular disease
 Cardiovascular events111.86.0(2.5–9.6)
  Conduction disturbances90.519.0(6.6–31.5)
  Bradycardia00.20
  Hypotension20.82.6(0–6.3)
  Cardiac arrest10.33.4(0–10.1)
With respiratory disease
 Respiratory events119.61.1(0.5–1.8)
  Acute bronchitis11.10.9(0–2.8)
  Chronic bronchitis00.20
  Bronchiolitis55.30.9(0.1–1.8)
  Bronchospasm23.30.6(0–1.5)
  Others41.92.1(0–4.1)
With metabolic disease
 Metabolic events00.50
With cardiovascular disease
 Death11.40.7(0–2.2)
  • Only the first events are taken into account. —, not applicable.

  • a Population with cardiovascular disease was used to calculate the ratio between the number of observed and the number of expected cardiovascular events and death. Population with respiratory disease was used to calculate the ratio between the number of observed and the number of expected respiratory events. Population with metabolic disease was used to calculate the ratio between the number of observed and the number of expected metabolic events.

  • b Indirect standardization on sex, age, and premature birth.