TABLE 2

Unadjusted Mean and Adjusted Bayley-III and DMC Neurodevelopment Domain Scores According to HIV Exposure in the Tshipidi Study, Botswana, 2010–2012

Bayley-III DomainNMean (SD)Unadjusted DifferenceAdjusted DifferenceEffect Size
HEUHUUEstimate (95% CI) PEstimate (95% CI) PCohen’s D (95% CI)
Cognitive65753.8 (3.4)53.0 (3.3)0.7 (0.2 to 1.2)<.010.6 (0.1 to 1.1).030.22 (−0.04 to 0.47)
Gross motor64252.6 (2.8)52.9 (2.7)−0.3 (−0.7 to 0.2).21−0.1 (−0.5 to 0.3).63−0.10 (−0.31 to 0.11)
Fine motor66837.3 (1.8)37.4 (1.8)−0.1 (−0.4 to 0.2).470.0 (−0.3 to 0.3).98−0.06 (−0.19 to 0.08)
Expressive language65225.0 (4.4)25.8 (4.1)−0.8 (−1.4 to −0.2).02−0.6 (−1.3 to 0.1).09−0.19 (−0.51 to 0.13)
Receptive language65221.1 (3.5)20.7 (3.3)0.3 (−0.2 to 0.9).210.3 (−0.3 to 0.8).350.10 (−0.16 to 0.36)
DMC domain
 Locomotor72332.2 (1.8)32.2 (1.8)−0.1 (−0.3 to 0.2).58−0.1 (−0.3 to 0.2).66−0.04 (−0.18 to 0.09)
 Fine motor71819.1 (2.3)19.4 (1.9)−0.3 (−0.6 to 0.0).05−0.1 (−0.4 to 0.2).63−0.15 (−0.30 to 0.01)
 Language72316.5 (2.6)16.5 (2.7)0.0 (−0.4 to 0.4).920.2 (−0.2 to 0.6).43−0.01 (−0.20 to 0.19)
 Personal-social72045.1 (3.9)44.5 (4.5)0.6 (0.0 to 1.2).060.7 (0.1 to 1.3).020.14 (−0.17 to 0.45)
  • Bayley-III: cognitive adjusted for maternal income and depression; gross motor adjusted for household access to water and food insecurity; fine motor adjusted for access to sanitation, maternal education, and housing type; expressive language adjusted for maternal education and household access to electricity; receptive language adjusted for maternal age. DMC: locomotor adjusted for maternal income and depression, fine motor adjusted for maternal education and social score, language adjusted for maternal education and maternal depression, personal-social adjusted for cooking method and maternal depression. CI, confidence interval.