Baseline Characteristics of Study Population (for Patients With Suspicion of Acute Infection)

Study Population n = 361
Age, y (mean, SD)4.1 (4.2)
Sex, female, n (%)170 (47)
Maximal temperature, °C (mean, SD)39.3 (0.8)
Received antibiotics, n (%)188 (52)
Time from symptom onset, d (median, IQR)4 (3)
Hospital admission, n (%)139 (47)
Hospitalization duration, d (median, IQR)0 (3)
Clinical syndrome, n (%)
 CNS infection3 (1)
 FWS125 (35)
 GE11 (3)
 LRTI56 (16)
 URTI114 (32)
 UTI17 (5)
 Other35 (10)
  • Clinical syndrome was the diagnosis recorded by the attending clinician at discharge (and was not modified in light of data accrued after discharge). CNS infections included meningitis. A diagnosis of FWS required a urine analysis with negative results. LRTIs included pneumonia and bronchiolitis. URTIs included acute tonsillitis, pharyngitis, sinusitis, acute otitis media, aphthous stomatitis, herpengina, retropharyngeal abscess, and scarlet fever. UTIs included cystitis and pyelonephritis. The “other” category included febrile convulsions, hepatitis, lymphadenitis, myositis, parotitis, sialoadenitis, and lymphadenopathy. CNS, central nervous system and encephalitis; FWS, fever without source; GE, gastroenteritis; IQR, interquartile range; LRTI, lower respiratory infection; URTI, upper respiratory infection; UTI, urinary tract infection.