TABLE 5

Test Characteristics of the YOS Score >6 and >10 as Well as Unstructured Clinician Suspicion ≥1% and ≥5% for the Identification of Infants With any SBI Overall Stratified by Patient Age (0–28 vs 29–60 d of Age)

Sensitivity, % (95% CI)Specificity, % (95% CI)Negative Predictive Value, % (95% CI)Likelihood Ratio +, % (95% CI)Likelihood Ratio, −, % (95% CI)
YOS > 60.39 (0.35–0.44)0.66 (0.64–0.67)0.91 (0.90–0.92)1.15 (1.01–1.30)0.92 (0.85–1.00)
 0–28 d0.40 (0.33–0.48)0.65 (0.62–0.68)0.88 (0.85–0.90)1.16 (0.96–1.40)0.91 (0.81–1.03)
 29–60 d0.38 (0.32–0.45)0.66 (0.64–0.68)0.93 (0.91–0.94)1.13 (0.96–1.33)0.93 (0.84–1.03)
YOS > 100.12 (0.09–0.15)0.90 (0.89–0.91)0.90 (0.89–0.91)1.12 (0.85–1.47)0.99 (0.95–1.02)
 0–28 d0.14 (0.09–0.20)0.89 (0.87–0.91)0.87 (0.85–0.89)1.30 (0.89–1.91)0.96 (0.91–1.02)
 29–60 d0.10 (0.06–0.14)0.90 (0.89–0.91)0.92 (0.91–0.93)0.96 (0.64–1.42)1.01 (0.96–1.05)
Suspicion > 1%0.76 (0.71–0.80)0.38 (0.36–0.39)0.94 (0.92–0.95)1.21 (1.14–1.29)0.65 (0.55–0.77)
 0–28 d0.74 (0.68–0.80)0.33 (0.31–0.36)0.90 (0.86–0.92)1.11 (1.01–1.22)0.77 (0.60–1.00)
 29–60 d0.77 (0.71–0.82)0.40 (0.38–0.41)0.95 (0.94–0.96)1.27 (1.18–1.37)0.59 (0.47–0.74)
Suspicion > 5%0.34 (0.30–0.39)0.80 (0.79–0.82)0.92 (0.91–0.93)1.76 (1.52–2.03)0.82 (0.76–0.87)
 0–28 d0.38 (0.31–0.45)0.76 (0.74–0.79)0.89 (0.87–0.91)1.59 (1.29–1.96)0.82 (0.73–0.92)
 29–60 d0.32 (0.26–0.38)0.82 (0.81–0.84)0.93 (0.92–0.94)1.80 (1.47–2.20)0.83 (0.76–0.90)