Association of AN Diagnosis Among Biopsied Women Without CD, Odds Ratio for Prior AN

OR for Previous ANa
Undergoing Biopsy (%)Matched Controls (%)Unadjusted OR for Previous AN (95% CI)Adjustedb OR for Previous AN (95% CI)
Inflammationc30/7455 (0.40)45/36 940 (0.12)3.35 (2.11–5.33)3.39 (2.09–5.49)
Normal mucosa but CD+ serologyd13/2307 (0.56)23/11 499 (0.20)2.86 (1.44–5.68)3.22 (1.49–6.96)
  • a HRs were estimated by using stratified Cox proportional-hazard regression and ORs were estimated with conditional logistic regression. Controls were matched for age, sex, calendar period of birth, and county of residence.

  • b Adjusted analyses accounting for education level, socioeconomic status, and type 1 diabetes.

  • c Small-intestinal inflammation without villous atrophy (Marsh I–II).

  • d Normal mucosa (Marsh 0) but with positive CD serology 180 days before and until 30 days after biopsy (antigliadin, antiendomysial, or antitransglutaminase antibodies).