TABLE 2

Univariate Factors Associated With Mortality Among Infants With Invasive Early-Onset Sepsis, Active Bacterial Core Surveillance, 2005 to 2014

CharacteristicDied (n = 165), % ExposedSurvived (n = 1319), % ExposedOR (95% CI)
Pathogen
 GBS22.437.5Referent
 E coli51.521.54.0 (2.7–6.1)
 Other26.141.01.1 (0.7–1.7)
Birth weight <1500 g75.816.715.6 (10.6–22.9)
Gestational age <34 wk82.426.013.3 (8.8–20.3)
Boy61.852.21.5 (1.1–2.1)
Black race45.536.61.4 (1.0–2.0)
Cesarean delivery59.444.41.8 (1.3–2.5)
Membrane rupture ≥18 h before delivery50.340.91.5 (1.1–2.0)
Exposure to intrapartum antibiotics71.547.32.8 (2.0–4.0)
Maternal intrapartum fever14.121.50.6 (0.4–1.0)
  • Multivariable analyses were stratified by birth weight because birth weight and pathogen had a significant interaction. The only variable significant at P < .05 on stratified multivariable analysis was pathogen type among infants >1500 g (E coli and “other” pathogens were associated with elevated odds of mortality compared with GBS, see Results section).