TABLE 5

Regression Coefficients (β) and 95% CIs for the Joint Effects of Maternal Prepregnancy BMI and GWG on Mammographic Density in the Daughter, in 646 Women Participating in the EDMD Study

n = 646Percent DensityDense Area
Model 1aModel 2bModel 1aModel 2b
β (95% CI)β (95% CI)β (95% CI)β (95% CI)
GWG and maternal prepregnancy BMI, categorized
 Maternal prepregnancy BMI <25 and gestational weight gain ≤10 kg284−1.4 (–4.1 to 1.4)−1.7 (–4.4 to 1.0)−3.5 (–7.4 to 0.5)−3.3 (–7.1 to 0.5)
 Maternal prepregnancy BMI ≥25 and gestational weight gain ≤10 kg110−2.1 (–6.1 to 1.8)−2.4 (–6.2 to 1.5)−0.3 (–6.2 to 5.6)−0.3 (–6.1 to 5.6)
 Maternal prepregnancy BMI <25 and gestational weight gain >10 kg1980.0 (Ref)0.0 (Ref)0.0 (Ref)0.0 (Ref)
 Maternal prepregnancy BMI ≥25 and gestational weight gain >10 kg54−4.5 (–9.4 to 0.4)−5.0 (–9.9 to –0.6)−2.9 (–9.9 to 4.0)−3.4 (–10.4 to 3.7)
  • a Adjusted for age at mammogram, site, and adult BMI.

  • b Adjusted for age at mammogram, site, adult BMI, maternal education, maternal prepregnancy BMI, race, and maternal smoking.