Distribution of Congenital Heart Defects Diagnosed Among 2588 Singleton Live-Born Infants With Down Syndrome, Born in Sweden 1992–2012

n% of Infants% of Defects
Any congenital heart defect
Type of congenital heart defecta
 Aortic arch abnormality903.56.5
 Tetralogy of Fallot361.42.6
 Transposition of the great arteries261.01.9
 Valve defects351.42.5
 Patent ductus arteriosus702.75.0
  • a Congenital heart defects were grouped into 4 main categories: complex defects (AVSD, aortic arch abnormalities, tetralogy of Fallot, transposition of the great arteries, single ventricular hearts); valve defects (aortic, pulmonary, and mitral-tricuspid valve defects); shunt defects (isolated VSD, isolated ASD, and isolated patent ductus arteriosus); others. See details in Methods.