TABLE 2

Risk of Bias Assessment of the Included Studies

Risk of Bias Assessment
Author (y) CountryRandom Sequence GenerationAllocation ConcealmentBlinding of Participant and StaffBlinding of Outcome AssessmentIncomplete Outcome DataSelective ReportingOther Bias
Tullus (1999) SwedenUnclearUnclearHigh riskHigh riskLow riskLow riskHigh riska
Tang (2010) ChinaLow riskUnclearHigh riskHigh riskUnclearUnclearUnclear
Ferrara (2014) ItalyLow riskbLow riskbHigh riskHigh riskbLow riskLow riskbLow riskb
Gökçe (2014) TurkeyLow riskLow riskLow riskLow riskHigh riskUnclearHigh riskc
  • a Study supported by the drug manufacturer.

  • b Additional information gathered from the corresponding author.

  • c Non–intention to treat analysis.