TABLE 1

Timeline of the Case

Day of lifeDay of IllnessHospital DayEventAcyclovir
51NAOnset of illnessNA
62NAAdmission to first hospitalInitiate acyclovir 20 mg/kg q8h
84NAHSV-1 detection by PCR20 mg/kg q24h
NAPE and CRRT (CVVHDF)20 mg/kg q24h
1061Transfer to our hospital20 mg/kg q24h
PE (6 h per day) and CVVHDF continued20 mg/kg q24h
1283NA20 mg/kg q8h
191510PE discontinued20 mg/kg q8h
252116Change CVVHDF to CVVHD20 mg/kg q12h
322823HSV-1 (serum) undetectableSwitch to suppression therapy
  • NA, not applicable