TABLE 1

Childhood and Adulthood Characteristics in Relation to Timing of IRH

NEarly-Childhood IRH (<5 Years)Lifetime IRH
AbsentPresentPAbsentPresentP
N1196181779597
Childhood characteristics
 Age, y6.2 ± 2.45.9 ± 2.5.236.1 ± 2.46.1 ± 2.5.95
 Male gender, %46.153.0.0834.663.2<.001
 LDL cholesterol, mmol/L13583.59 ± 0.83.53 ± 0.79.523.60 ± 0.783.56 ± 0.81.85
 HDL cholesterol, mmol/L13581.58 ± 0.311.56 ± 0.30.491.56 ± 0.301.60 ± 0.31.08
 Triglycerides, mmol/L13580.60 ± 0.260.59 ± 0.24.470.61 ± 0.250.59 ± 0.26.84
 BMI, kg/m2136015.9 ± 1.716.1 ± 2.1.1115.9 ± 1.715.9 ± 1.9.65
 Systolic BP, mm Hg1347107 ± 10107 ± 11.82107 ± 10107 ± 11.86
 Diastolic BP, mm Hg134767 ± 967 ± 10.9667 ± 967 ± 9.71
 hsCRP, mg/L10681.0 ± 2.91.5 ± 3.8.101.0 ± 3.11.1 ± 2.8.70
 Insulin, mU/L13376.4 ± 3.96.4 ± 4.4.586.4 ± 3.96.4 ± 3.9.89
 Birth weight, kg12983.51 ± 0.523.48 ± 0.64.363.49 ± 0.533.52 ± 0.55.83
 Physical activity, z score12280.02 ± 1.00−0.09 ± 1.00.280.01±1.03−0.01 ± 0.96.63
 Mother's BMI, kg/m2134223.0 ± 3.723.0 ± 4.4.9323.0 ± 3.723.1 ± 4.0.27
 Father's BMI, kg/m2136623.8 ± 5.123.4 ± 6.0.4623.9 ± 4.923.5 ± 5.6.53
 Parental smoking, %131148.954.9.1447.352.8.06
 Family incomea136926.4 ± 13.223.9 ± 13.0.0226.3 ± 13.425.8 ± 13.0.45
Adulthood characteristics
 Age, y35.2 ± 4.334.6 ± 4.6.1035.3 ± 4.234.9 ± 4.5.05
 LDL cholesterol, mmol/L13653.14 ± 0.813.04 ± 0.75.083.10 ± 0.793.15 ± 0.80.55
 HDL cholesterol, mmol/L13651.32 ± 0.331.27 ± 0.37.301.34 ± 0.331.26 ± 0.33.49
 Triglycerides, mmol/L13651.32 ± 1.321.36 ± 0.87.861.25 ± 1.361.41 ± 1.13.38
 BMI, kg/m2137425.6 ± 4.826.7 ± 5.4.00525.4 ± 4.826.3 ± 5.0.01
 Waist circumference, cm137488.3 ± 13.791.1 ± 14.7.0386.8 ± 13.491.1 ± 14.0.003
 Systolic BP, mm Hg1374117 ± 13118 ± 13.98116 ± 13118 ± 13.23
 Diastolic BP, mm Hg137474 ± 1173 ± 11.3572 ± 1174 ± 10.51
 hsCRP, mg/L13701.8 ± 3.11.7 ± 2.5.731.8 ± 2.71.8 ± 3.4.61
 Insulin, mU/L13719.3 ± 11.29.3 ± 7.7.959.0 ± 8.79.8 ± 13.4.22
 Glucose, mmol/L13715.27 ± 0.955.25 ± 1.19.685.19 ± 0.745.37 ± 1.24.02
 Alcohol consumption, drinks/wk13256.2 ± 10.87.2 ± 12.4.565.1 ± 8.58.0 ± 13.4.04
 Education, y136215.6 ± 3.614.9 ± 3.6.0415.8 ± 3.615.0 ± 3.4.009
  • Data are presented as means ± SDs unless stated otherwise. Characteristics values are unadjusted. P values in continuous risk factors from regression analyses were adjusted for age and gender. Logistic regression with age and gender adjustment was used for categorical variables. BP, blood pressure; hsCRP, high-sensitivity C-reactive protein.

  • a Finnish currency in 1980 was converted to thousand euros and the levels adjusted to correspond to 2011 levels.