TABLE 2

Regression Models for Cross-sectional Lung Function and LRIs During the First 3 Years of Life

LRIsFEV1, mLFVC, mLFEV1:FVC Ratio, %FEF25–75, mL/sFEF25–75:FVC Ratio, %
B (SE)PB (SE)PB (SE)PB (SE)PB (SE)P
Prealbuterol lung function
 Age 11 years (N = 548)
  No LRIRefRefRefRefRef
  Pneumonia−109.74 (46.71).0192.05 (53.75).970−4.30 (1.07)<.001−415.45 (105.29)<.001−16.46 (4.07)<.001
  Other LRIs−64.87 (23.46).006−56.37 (27.00).037−0.72 (0.54).179−147.40 (52.88).006−4.10 (2.04).045
 Age 16 years (N = 434)
  No LRIRefRefRefRefRef
  Pneumonia−158.51 (76.81).04056.10 (92.44).544−4.20 (1.25).001−460.97 (149.66).002−10.94 (3.77).004
  Other LRIs−83.61 (40.64).040−19.18 (48.91).695−1.48 (0.66).026−212.63 (79.43).008−4.79 (2.00).017
 Age 22 years (N = 397)
  No LRIRefRefRefRefRef
  Pneumonia−260.93 (87.45).003−97.42 (97.22).317−3.84 (1.42).007−523.42 (187.23).005−9.42 (4.27).028
  Other LRIs−27.90 (43.38).52133.92 (48.23).482−1.30 (0.70).065−117.09 (92.87).208−3.70 (2.12).082
 Age 26 years (N = 297)
  No LRIRefRefRefRefRef
  Pneumonia−163.02 (99.30).102−23.87 (110.57).829−3.23 (1.51).034−507.60 (216.73).020−11.14 (4.91).024
  Other LRIs−119.77 (52.08).022−119.18 (57.99).041−0.63 (0.79).427−151.45 (113.67).184−1.92 (2.57).456
Postalbuterol lung function
 Age 11 years (N = 534)
  No LRIRefRefRefRefRef
  Pneumonia−43.33 (44.40).33016.66 (53.00).753−2.09 (1.01).038−281.22 (101.84).006−11.15 (4.09).007
  Other LRIs−22.39 (22.62).323−16.53 (26.99).540−0.40 (0.51).434−103.83 (51.87).046−3.73 (2.08).073
 Age 16 years (N = 425)
  No LRIRefRefRefRefRef
  Pneumonia−116.67 (76.90).13042.11 (91.63).646−3.17 (1.03).002−427.17 (149.75).005−10.55 (3.72).005
  Other LRIs−66.62 (41.07).106−35.04 (48.98).475−0.86 (0.55).119−187.95 (80.08).019−4.13 (1.99).039
 Age 22 years (N = 393)
  No LRIRefRefRefRefRef
  Pneumonia−234.25 (80.84).004−92.95 (96.86).338−3.14 (1.16).007−589.87 (178.22).001−10.27 (4.25).016
  Other LRIs−24.05 (40.27).55111.09 (48.25).818−0.83 (0.58).154−138.40 (89.05).121−3.63 (2.12).088
 Age 26 years (N = 286)
  No LRIRefRefRefRefRef
  Pneumonia−142.10 (97.46).1460.70 (144.20).995−3.03 (1.32).022−522.03 (225.51).021−11.39 (5.20).029
  Other LRIs−119.02 (50.93).020−125.12 (59.68).037−0.23 (0.69).742−110.35 (118.21).351−0.13 (2.72).963
  • All models included gender, height, race/ethnicity, and LRIs. B, model coefficient; Ref, reference group in the model.