TABLE 2

Characteristics of the Study Population in Relation to Exposure to Antibiotics at <24 Months

CharacteristicsBoys (n = 6114)Girls (n = 5948)
ExposedUnexposedPaExposedUnexposedPa
n (%)4828 (79.0)1286 (21.0%)4408 (74.1%)1540 (25.9%)
Number of measurements per child14 (1–48)11 (1–28)<0.00114 (1–36)12 (1–32)<0.001
Age at primary end point (y)b2.06 (2.00–6.11)2.05 (2.00–5.50)NS2.06 (2.00–6.19)2.05 (2.00–5.24)NS
zBMIb,c0.05 (0.99)−0.09 (1.02)<0.0010.05 (1.01)−0.04 (1.00)<0.01
zHFAb,c0.00 (0.98)−0.08(1.00)<0.01−0.02 (0.99)−0.05 (1.01)NS
Perinatal variables
 Gestational age (wks)40.1 (37.0–43.9)40.1 (37.0–42.9)NS40.3 (37.0–43.0)40.3 (37.0–42.7)NS
 Birth length (cm)51.1 (1.95)50.9 (1.96)<0.0150.3 (1.89)50.2 (1.82)NS
 Birth length z-scored0.07 (1.00)−0.01 (1.01)<0.010.10 (1.00)0.08 (0.97)NS
 Birth weight (kg)3.65 (0.48)3.61 (0.48)<0.053.55 (0.46)3.51 (0.45)<0.01
 Birth weight z-scored−0.07 (0.97)−0.12 (1.00)NS−0.02 (1.01)−0.08 (0.96)<0.05
  • Values are expressed as the median (range) or mean (SD).

  • a Unadjusted difference.

  • b First measurement at the age of ≥24 mo.

  • c Finnish growth reference.18

  • d Finnish growth reference for birth size.20