Table 5.

Definition of a Positive Mantoux Skin Test (5TU-PPD) in Children*45

Reaction ≥5 mm
 Children in close contact with persons who have known or suspected infectious cases of TB:
  Households with active or previously active cases if (1) treatment cannot be verified as adequate before exposure, (2) treatment was initiated after contact with the child occurred, or (3) reactivation is suspected.
 Children suspected to have tuberculous disease:
  Chest radiograph shows active or previously active TB
  Clinical evidence of TB
 Children with immunosuppressive conditions or HIV infection
Reaction ≥10 mm
 Children at increased risk of dissemination from:
  Young age: <4 y
  Other medical risk factors, including Hodgkin's disease, lymphoma, diabetes mellitus, chronic renal failure, and malnutrition
 Children with increased environmental exposure:
  Born or with parents born in regions of the world where TB is endemic
  Frequent exposure to adults who are HIV-infected, homeless, users of intravenous and other street drugs, poor and medically indigent city dwellers, residents of nursing homes, incarcerated or institutionalized persons, or migrant farm workers
Reaction ≥15 mm
 Children ≥4 y of age without any risk factors
  • * The Mantoux skin test contains 5 tuberculin units of purified protein derivative (5TU-PPD). These recommendations should apply regardless of whether bacille Calmette-Guérin (BCG) has been previously administered. TB, tuberculosis; HIV, human immunodeficiency virus.

  • Including immunosuppressive dose of corticosteroids.