FIGURE 2

A, Validation of MxA as a marker of viral infection. Blood MxA values of uninfected patients (controls, n = 89), patients with confirmed viral infection (n = 56), and patients with confirmed bacterial infection (n = 48) of the validation group. The horizontal bar shows the median. Because of the logarithmic scale, MxA values were transformed as follows for graphical representation: value shown in the graph = MxA value + 1. P < .0001 for the comparison of all groups (Kruskal-Wallis test) and P < .05 for all pairwise comparisons (Dunn’s multiple comparison test). B, ROC analysis of MxA for the differentiation of uninfected patients from patients with confirmed viral infection (validation group). C, ROC analysis of MxA for the differentiation of patients with confirmed viral infection from patients with confirmed bacterial infection (validation group). AUC, area under the ROC curve.