TABLE 1

IRRs by Cesarean Delivery in the 35-Year Period 1977–2011 Following 1.9 Million Term Children in the Age Span 0 to 15 Years

CasesaIRR (95% Confidence Interval); PPARF (Cases)
Asthmaa103 8221.23 (1.21–1.25); P < .00013.07 (3187)
Asthma >5 yb48 8581.16 (1.13–1.19); P < .00012.19 (1070)
Systemic connective tissue disorders74981.11 (1.04–1.19); P = .00211.53 (115)
Juvenile arthritis69461.10 (1.02–1.18); P = .01171.34 (93)
Diabetes type 161361.01 (0.93–1.10); P = .82d
Inflammatory bowel diseases26971.20 (1.06–1.36); P = .0042.70 (73)
Immune deficiencies25891.46 (1.32–1.62); P < .00016.09 (158)
Celiac disease19440.99 (0.87–1.14); P = .89d
Leukemia16311.17 (1.00–1.36); P = .0482.31 (38)
Psoriasis13060.98 (0.81–1.18); P = .81d
Arm fracturea,c77 4900.99 (0.96–1.01); P = .19d
  • Cases are defined by first in- or outpatient admission to a hospital in Denmark. IRRs are adjusted for age, calendar year, birth weight, parity, gender, season of birth, maternal age, and maternal illness. The PARF is calculated based on an overall prevalence of 14% cesarean deliveries for diseases with significant association to cesarean delivery.

  • a Attained age and calendar year included in 1-y categories.

  • b Attained calendar year included in 3-y and age in 6-y categories.

  • c Not adjusted for maternal disease.

  • d PARF is not calculated for insignificant associations.