TABLE 3

Clinical Effects Related to Laundry Detergent Pod Exposures Among Children Younger Than 6 Years by Exposure Route, NPDS 2012–2013

Clinical EffectsSingle RouteMultiple RoutesClinical Effect Total, n (%a)
Ingestion, n (%a)Ocular, n (%a)Dermal, n (%a)Aspiration, n (%a)Ingestion+b, n (%a)Otherc, n (%a)
Cardiac effects
 Tachycardia104 (0.8)2 (0.2)9 (15.3)9 (0.5)124 (0.7)
Dermal effects
 Erythema/flushed91 (0.7)34 (2.7)49 (39.2)1 (1.7)95 (5.3)50 (17.5)320 (1.9)
 Edema26 (0.2)140 (11.3)9 (7.2)66 (3.7)45 (15.7)286 (1.7)
 Irritation/pain31 (0.2)55 (4.4)38 (30.4)71 (4.0)33 (11.5)228 (1.3)
 Rash105 (0.8)5 (0.4)27 (21.6)83 (4.6)7 (2.4)227 (1.3)
 Pallor46 (0.3)6 (0.3)52 (0.3)
 Burns (superficial)5 (0.0)8 (0.6)12 (9.6)16 (0.9)5 (1.7)46 (0.3)
Gastrointestinal effects
 Vomiting7694 (56.0)4 (0.3)2 (1.6)48 (81.4)518 (29.0)2 (0.7)8269 (48.0)
 Nausea670 (4.9)1 (1.7)74 (4.1)1 (0.3)746 (4.3)
 Oral irritation478 (3.5)3 (0.2)2 (3.4)83 (4.6)1 (0.3)567 (3.3)
 Throat irritation341 (2.5)4 (6.8)46 (2.6)391 (2.3)
 Diarrhea296 (2.2)1 (1.7)33 (1.8)330 (1.9)
 Abdominal Pain145 (1.1)2 (0.2)1 (0.8)12 (0.7)160 (0.9)
 Dysphagia25 (0.2)4 (0.2)29 (0.2)
 Oral burns (including lips)25 (0.2)3 (0.2)28 (0.2)
 Oropharyngeal edema25 (0.2)2 (0.1)27 (0.2)
Neurologic effects
 Drowsiness/lethargy1074 (7.8)3 (0.2)13 (22.0)106 (5.9)3 (1.0)1199 (7.0)
 Agitated/irritable120 (0.9)8 (0.6)4 (6.8)31 (1.7)1 (0.3)164 (1.0)
 Coma24 (0.2)3 (5.1)3 (0.2)30 (0.2)
Ocular effects
 Irritation/pain129 (0.9)971 (78.4)2 (1.6)552 (30.9)226 (79.0)1880 (10.9)
 Red eye/conjunctivitis68 (0.5)627 (50.6)329 (18.4)132 (46.2)1156 (6.7)
 Lacrimation17 (0.1)154 (12.4)50 (2.8)36 (12.6)257 (1.5)
 Corneal abrasion19 (0.1)145 (11.7)48 (2.7)26 (9.1)238 (1.4)
 Burns5 (0.0)34 (2.7)18 (1.0)9 (3.1)66 (0.4)
 Photophobia1 (0.0)22 (1.8)6 (0.3)8 (2.8)37 (0.2)
Respiratory effects
 Cough/choke1998 (14.6)1 (0.1)2 (1.6)39 (66.1)249 (13.9)1 (0.3)2290 (13.3)
 Dyspnea171 (1.2)10 (16.9)18 (1.0)199 (1.2)
 Bronchospasm120 (0.9)7 (11.9)11 (0.6)138 (0.8)
 X-ray findings(+)89 (0.6)16 (27.1)7 (0.4)112 (0.7)
 Hyperventilation/tachypnea73 (0.5)6 (10.2)2 (0.1)81 (0.5)
 Respiratory depression60 (0.4)6 (10.2)2 (0.1)68 (0.4)
 Pneumonitis23 (0.2)6 (10.2)3 (0.2)32 (0.2)
Miscellaneous effects
 Other629 (4.6)75 (6.1)2 (1.6)19 (32.2)138 (7.7)20 (7.0)884 (5.1)
 Excess secretions207 (1.5)8 (0.6)10 (16.9)27 (1.5)1 (0.3)253 (1.5)
 Fever/hyperthermia78 (0.6)5 (8.5)8 (0.4)91 (0.5)
 Acidosis42 (0.3)4 (6.8)3 (0.2)49 (0.3)
Exposure route total13 730123812559178828617 230
  • Only clinical effects with a number of cases representing ≥0.2% of all exposures are presented in this table. —, no clinical effect.

  • a Percentages relate to each exposure route total and will not sum to 100.0%, because some patients experienced none or more than 1 clinical effect.

  • b Ingestion+ includes multiple exposure routes with ingestion.

  • c Other includes multiple exposure routes without ingestion.