TABLE 1

Cyanotic Congenital Heart Disease or Aortic Arch Obstruction Diagnosed in Newborns at BWH or Referred From Other Hospitals to the CICU at BCH in the First 10 Weeks After Birth During the Study Period

Diagnosis	Born at BWH			Born at Other Hospitals
Diagnosis	Prenatal	Postnatal	% Prenatal	Prenatal	Postnatal	% Prenatal
Lesions selected to be screened by AAP
Hypoplastic left heart	16	0		2	3
Pulmonary atresia-intact ventricular septum	4	0		0	4^a
Tetralogy of Fallot^b	17	0		9	6
dextro-transposition of the great arteries^c	18	0		2	10
Tricuspid atresia	4	0		2	0
Total anomalous pulmonary venous connection	0^d	0		0	7
Truncus arteriosus	4	0		0	0
Total	63	0	100	15	30	33
Aortic arch obstruction
Coarctation of the aorta	20	0		7	14
Interrupted aortic arch, ventricular septal defect	6	1		0	2
Total	26	1	96	7	16	30
Other cyanotic congenital heart disease	22^e	0	100	6^f	7^g	46
Suspected aortic arch obstruction not confirmed by postnatal echocardiography^h	15	—		1	—

—, not applicable.
↵^a Two patients had critical pulmonary stenosis with near atresia.
↵^b Eighteen with pulmonary stenosis, 11 with pulmonary atresia, 2 with absent pulmonary valve, 1 with complete atrioventricular canal.
↵^c Twenty-one with intact ventricular septum, 3 with ventricular septal defect, 6 with ventricular septal defect and pulmonary stenosis.
↵^d Total anomalous pulmonary venous connection did occur in 3 patients with heterotaxy and atrioventricular canal defect that was detected prenatally, and are listed in the “Other cyanotic congenital heart disease” section.
↵^e Heterotaxy (total 7) with atrioventricular canal and total anomalous pulmonary venous connection (3), unbalanced atrioventricular canal and hypoplastic left ventricle (2), or atrioventricular canal, double outlet right ventricle, pulmonary stenosis (2); complex congenital heart disease with single ventricle physiology (5); critical aortic stenosis with fetal intervention (4); unbalanced complete atrioventricular canal (2); Ebstein anomaly of the tricuspid valve (1); pulmonary atresia with large apical muscular ventricular septal defect (1); hypoplastic right ventricle, ventricular septal defect, pulmonary stenosis (1); double outlet right ventricle, superior-inferior ventricles, crisscross atrioventricular valves (1).
↵^f Heterotaxy (total 2) with double outlet right ventricle, ventricular septal defect, crisscross atrioventricular valves, pulmonary stenosis (1), or tetralogy of Fallot and malposed atrial septum (1); Ebstein anomaly of the tricuspid valve (1); dysplastic tricuspid valve (1); right dominant unbalanced atrioventricular canal, small left ventricle, coarctation of the aorta (1); double outlet right ventricle, transposition of the great arteries, pulmonary stenosis (1).
↵^g Critical aortic stenosis (1); arterial tortuosity syndrome and midaortic syndrome (1); pericardial teratoma compressing airway (1); pulmonary glycogenosis and pulmonary vein stenosis (1); vascular ring (right aortic arch with aberrant left subclavian artery compressing airway and multiple ventricular septal defects) (1); Ebstein anomaly of the tricuspid valve (1); arcade mitral valve associated with severe mitral regurgitation (1).
↵^h Left-ventricular–right-ventricular size discrepancy or aortic arch hypoplasia noted on fetal echocardiography.